Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.32 |
| ▸ | CLK1 | P49759 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.32 |
| ▸ | MLYCD | O95822 | 1/20 | 0.31 |
| ▸ | NNMT | P40261 | 2/20 | 0.31 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28781309 | 0.83 | TRPM8 (0.37) | TRPM8CLK1DYRK1ADYRK1BMLYCD | |
| SCHEMBL28876491 | 0.79 | NNMT (0.33) | MEN1KMT2ANNMT | |
| SCHEMBL15927726 | 0.78 | MEN1 (0.38) | MEN1KMT2ATDP1TRPM8CLK1 | |
| SCHEMBL9280675 | 0.77 | KMT2A (0.43) | MEN1KMT2ATDP1TRPM8CLK1 | |
| SCHEMBL28931441 | 0.72 | NNMT (0.45) | MEN1KMT2ANNMT | |
| SCHEMBL23089698 | 0.72 | RAB9A (0.41) | MEN1KMT2ATDP1TRPM8CLK1 | |
| SCHEMBL15874233 | 0.72 | MEN1 (0.40) | MEN1KMT2ATDP1TRPM8CLK1 | |
| SCHEMBL29150549 | 0.71 | PARP1 (0.31) | NCEH1 | |
| SCHEMBL28876653 | 0.70 | ALOX5 (0.32) | NCEH1 | |
| SCHEMBL28737030 | 0.70 | NNMT (0.33) | MEN1KMT2ANNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114945366-A | HPK1 antagonists and uses thereof | 林伯士萨顿公司 | 2022-08-26 | — | — | CN | disclosed |