Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL288966 | 1.00 | ALDH1A1 (0.42) | ALDH1A1NR3C1TSHRNOS1HSD17B10 | |
| SCHEMBL27815006 | 1.00 | ALDH1A1 (0.42) | ALDH1A1NR3C1TSHRNOS1HSD17B10 | |
| SCHEMBL3180703 | 0.82 | ALDH1A1 (0.44) | ALDH1A1NR3C1HTTNPC1MEN1 | |
| SCHEMBL28647935 | 0.81 | ALDH1A1 (0.42) | ALDH1A1NR3C1HTTNPC1MEN1 | |
| SCHEMBL18074328 | 0.77 | ALDH1A1 (0.39) | ALDH1A1NR3C1HTTMEN1KMT2A | |
| SCHEMBL21552486 | 0.77 | ALDH1A1 (0.39) | ALDH1A1NR3C1HTTNPC1MEN1 | |
| SCHEMBL28639887 | 0.76 | ALDH1A1 (0.41) | ALDH1A1NR3C1TSHRNOS1HSD17B10 | |
| SCHEMBL2355729 | 0.75 | — | — | |
| SCHEMBL10714349 | 0.75 | ALDH1A1 (0.38) | ALDH1A1NR3C1TSHRNOS1HSD17B10 | |
| SCHEMBL9372859 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 464 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3970801-A1 | RAS INHIBITORY PEPTIDE | Ichimaru Pharcos Co., Ltd. (JP) | 2022-03-23 | — | — | EP | claimed |
| CN-113727991-A | Ras inhibitory peptide | 一丸自然美健有限公司 | 2021-11-30 | — | — | CN | claimed |
| WO-2020230780-A1 | Ras INHIBITORY PEPTIDE | 一丸ファルコス株式会社 | 2020-11-19 | — | — | WO | claimed |
| WO-2020081958-A2 | COMPOSITIONS AND METHODS FOR IDENTIFYING MUTATIONS OF GENES OF MULTI-GENE SYSTEMS HAVING IMPROVED FUNCTION | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2020-04-23 | — | — | WO | claimed |
| US-20200095275-A1 | SITE-SELECTIVE FUNCTIONALIZATION OF PROTEINS USING TRACELESS AFFINITY LABELS | KRANTZ ALEXANDER (US) | 2020-03-26 | — | — | US | claimed |
| CN-109294966-A | A kind of the Corynebacterium glutamicum recombinant bacterium and its construction method of high yield L-Leu | 江南大学 | 2019-02-01 | — | — | CN | claimed |
| EP-3413921-A1 | SITE-SELECTIVE FUNCTIONALIZATION OF PROTEINS USING TRACELESS AFFINITY LABLES | Krantz, Alexander (US) | 2018-12-19 | — | — | EP | claimed |
| CN-108841758-A | Corynebacterium glutamicum mutant and its application in L-Leu production | 大连医诺生物股份有限公司 | 2018-11-20 | — | — | CN | claimed |
| US-10017481-B2 | Conformationally constrained, fully synthetic macrocyclic compounds | POLYPHOR AG (CH) | 2018-07-10 | — | — | US | claimed |
| EP-2836485-B1 | CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS | POLYPHOR AG (CH) | 2018-01-10 | — | — | EP | claimed |
| US-20120270881-A1 | CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS | POLYPHOR AG (CH) | 2012-10-25 | — | — | US | claimed |
| EP-2499148-A2 | CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS | Polyphor Ag (CH) | 2012-09-19 | — | — | EP | claimed |
| US-20120202821-A1 | CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS | POLYPHOR AG (CH) | 2012-08-09 | — | — | US | claimed |
| WO-2011014973-A2 | CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS | POLYPHOR AG (CH) | 2011-02-10 | — | — | WO | claimed |
| US-7419810-B2 | Arginine repressor deficient strain of coryneform bacterium and method for producing L-arginine | AJINOMOTO CO., INC. (JP) | 2008-09-02 | — | — | US | claimed |
| US-20070031946-A1 | Arginine repressor deficient strain of coryneform bacterium and method for producing L-arginine | AJINOMOTO CO., INC. (JP) | 2007-02-08 | — | — | US | claimed |
| US-7160705-B2 | Arginine repressor deficient strain of coryneform bacterium and method for producing L-arginine | AJINOMOTO CO., INC. (JP) | 2007-01-09 | — | — | US | claimed |
| US-4393135-A | GENETICALLY ENGINEERED ESCHERICHIA | AJINOMOTO COMPANY INCORPORATED (JP) | 1983-07-12 | — | — | US | claimed |
| US-4388405-A | ESCHERICHIA INCORPORATED WITH HYBRID PLASMID | AJINOMOTO COMPANY INCORPORATED (JP) | 1983-06-14 | — | — | US | claimed |
| EP-0030391-A2 | Method for producing L-glutamic acid by fermentation and a method for producing a new microorganism | AJINOMOTO CO., INC. (JP) | 1981-06-17 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200095275-A1 | SITE-SELECTIVE FUNCTIONALIZATION OF PROTEINS USING TRACELESS AFFINITY LABELS | MYCBP, FABP3, STUB1 | ALDH1A1 2572/4885NR3C1 3657/4885TSHR 2656/4885 |
| US-20120202821-A1 | CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS | HTR2B, MC1R, HTR1A | ALDH1A1 4268/4885NR3C1 807/4885TSHR 140/4885 |
| US-10017481-B2 | Conformationally constrained, fully synthetic macrocyclic compounds | CTSE, CTSB, CTSS | ALDH1A1 4415/4885NR3C1 1069/4885TSHR 28/4885 |
| US-20120270881-A1 | CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS | KCNB1, KCNAB1, KCNMB1 | ALDH1A1 4142/4885NR3C1 1892/4885TSHR 968/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.