Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 3/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.34 |
| ▸ | FABP7 | O15540 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 6/20 | 0.34 |
| ▸ | CTSL | P07711 | 3/20 | 0.34 |
| ▸ | CTSB | P07858 | 3/20 | 0.34 |
| ▸ | CTSH | P09668 | 2/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7433217 | 0.88 | MDM2 (0.34) | TLR2KMT2ACASP3CTSK | |
| SCHEMBL27527132 | 0.86 | CASP3 (0.38) | TLR2PPARGPPARAKMT2ACASP3 | |
| SCHEMBL289035 | 0.78 | FABP5 (0.40) | PPARGPPARAKMT2ACASP3FABP5 | |
| SCHEMBL4740141 | 0.74 | KMT2A (0.38) | TLR2KMT2ACASP3FABP5FABP7 | |
| SCHEMBL12466708 | 0.73 | KMT2A (0.49) | TLR2KMT2ACASP3FABP5FABP7 | |
| SCHEMBL2401697 | 0.72 | KMT2A (0.46) | TLR2KMT2ACASP3FABP5FABP7 | |
| SCHEMBL27042592 | 0.72 | CASP3 (0.35) | PPARGPPARAKMT2ACASP3FABP5 | |
| SCHEMBL7438477 | 0.72 | TLR2 (0.51) | TLR2KMT2ACASP3 | |
| SCHEMBL25301402 | 0.71 | TLR2 (0.40) | TLR2PPARGPPARAKMT2ACASP3 | |
| SCHEMBL1556697 | 0.71 | OPRM1 (0.38) | KMT2ACASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187905-B1 | PEPTIDE COMPOUND WHICH INHIBITS VIRAL PROTEINASES; VIRICIDES FOR HEPATITIS C, HEPATITIS G, AND HUMAN GB VIRUSES | HOFFMANN-LA ROCHE INC. | 2001-02-13 | — | — | US | disclosed |