SCHEMBL2892268

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1165022	0.84	CHRNA1 (0.36)	ALDH1A1CHRNA1CHRNA7CHRNB2CHRNA4
	SCHEMBL2893284	0.78	ALDH1A1 (0.42)	ALDH1A1PSEN1PSEN2APH1BNCSTN
	SCHEMBL119406	0.76	ALDH1A1 (0.37)	ALDH1A1PSEN1PSEN2APH1BNCSTN
	SCHEMBL2892730	0.76	MT-CO2 (0.39)	ALDH1A1PSEN1PSEN2APH1BNCSTN
	SCHEMBL29728033	0.76	ALDH1A1 (0.37)	ALDH1A1PSEN1PSEN2APH1BNCSTN
	SCHEMBL14101263	0.76	LMNA (0.34)	ALDH1A1LMNAL3MBTL1MEN1KMT2A
	SCHEMBL15407589	0.74	PSEN1 (0.38)	ALDH1A1PSEN1PSEN2APH1BNCSTN
	SCHEMBL1165495	0.71	LMNA (0.35)	ALDH1A1CHRNA1CHRNA7CHRNB2CHRNA4
	SCHEMBL14101254	0.71	CHRNA1 (0.41)	ALDH1A1CHRNA1CHRNA7CHRNB2CHRNA4
	SCHEMBL14101262	0.70	ALDH1A1 (0.38)	ALDH1A1CHRNA1CHRNA7CHRNB2CHRNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.