Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | WEE1 | P30291 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ME3 | Q16798 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14922328 | 0.76 | ALDH1A1 (0.52) | SMN1; SMN2ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL14922259 | 0.76 | ADRB1 (0.52) | ALDH1A1KDM4EUSP2HTR3EHTR3B | |
| SCHEMBL28933199 | 0.75 | CA1 (0.44) | NAMPTSMYD3ALDH1A1MEN1KMT2A | |
| SCHEMBL5545942 | 0.74 | SMYD3 (0.44) | NAMPTSMYD3L3MBTL3L3MBTL1WEE1 | |
| SCHEMBL28704613 | 0.74 | JAK2 (0.49) | SMN1; SMN2ALDH1A1GAAKDM4EMAPT | |
| SCHEMBL3441371 | 0.72 | MAPT (0.57) | SMYD3SMN1; SMN2L3MBTL3L3MBTL1ALDH1A1 | |
| SCHEMBL16669437 | 0.71 | L3MBTL3 (0.44) | SMYD3L3MBTL3L3MBTL1MEN1KMT2A | |
| SCHEMBL8338229 | 0.71 | LTA4H (0.44) | NAMPTSMYD3L3MBTL3L3MBTL1ALDH1A1 | |
| SCHEMBL8724121 | 0.71 | L3MBTL1 (0.44) | NAMPTSMYD3L3MBTL3L3MBTL1ALDH1A1 | |
| SCHEMBL5545948 | 0.71 | TDP1 (0.51) | SMYD3L3MBTL3L3MBTL1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114014866-A | 5, 7-dihydrofuro [3,4-d ] pyrimidine compound and preparation method and application thereof | 山东大学 | 2022-02-08 | — | — | CN | disclosed |