Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29929924 | 0.78 | MAP3K7 (0.47) | MAP4K1 | |
| SCHEMBL28927885 | 0.77 | MAP4K3 (0.43) | MAP4K1KDM1A | |
| SCHEMBL28927875 | 0.75 | GPR119 (0.39) | KDM1A | |
| SCHEMBL28633555 | 0.72 | MAP4K1 (0.42) | MAP4K1GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL29929741 | 0.70 | MAP4K1 (0.51) | MAP4K1 | |
| SCHEMBL28631971 | 0.70 | MAP4K1 (0.51) | MAP4K1 | |
| SCHEMBL28927864 | 0.70 | PIM1 (0.43) | MAP4K1 | |
| SCHEMBL28927866 | 0.70 | MAP4K1 (0.46) | MAP4K1 | |
| SCHEMBL28962175 | 0.70 | KDM1A (0.45) | MAP4K1KDM1A | |
| SCHEMBL28925081 | 0.66 | MAP4K1 (0.43) | MAP4K1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115244050-A | Novel HPK1 inhibitor and preparation method and application thereof | 轶诺(浙江)药业有限公司 | 2022-10-25 | — | — | CN | disclosed |