Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K7 | O43318 | 16/20 | 0.47 |
| ▸ | TAB1 | Q15750 | 16/20 | 0.47 |
| ▸ | MAP4K3 | Q8IVH8 | 3/20 | 0.45 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28634046 | 0.88 | MAP4K3 (0.59) | MAP3K7TAB1MAP4K3 | |
| SCHEMBL28636439 | 0.87 | MAP3K7 (0.51) | MAP3K7TAB1MAP4K3 | |
| SCHEMBL28927859 | 0.84 | MAP3K7 (0.45) | MAP3K7TAB1MAP4K3 | |
| SCHEMBL28962176 | 0.78 | MAP4K1 (0.38) | MAP4K1 | |
| SCHEMBL28927885 | 0.76 | MAP4K3 (0.43) | MAP3K7TAB1MAP4K3MAP4K1 | |
| SCHEMBL28927875 | 0.76 | GPR119 (0.39) | MAP3K7TAB1 | |
| SCHEMBL28962175 | 0.73 | KDM1A (0.45) | MAP4K3MAP4K1 | |
| SCHEMBL29929741 | 0.73 | MAP4K1 (0.51) | MAP4K1 | |
| SCHEMBL28631971 | 0.73 | MAP4K1 (0.51) | MAP4K1 | |
| SCHEMBL28633555 | 0.71 | MAP4K1 (0.42) | MAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115244050-A | Novel HPK1 inhibitor and preparation method and application thereof | 轶诺(浙江)药业有限公司 | 2022-10-25 | — | — | CN | disclosed |