Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 4/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MLYCD | O95822 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13865453 | 0.74 | CYP2C19 (0.42) | SMN1; SMN2OPRM1DRD3DRD2DRD4 | |
| SCHEMBL3626452 | 0.74 | L3MBTL1 (0.42) | SMN1; SMN2POLBLMNAALDH1A1 | |
| SCHEMBL5798680 | 0.72 | KCNN4 (0.40) | SMN1; SMN2POLBOPRM1DRD3DRD2 | |
| SCHEMBL13050382 | 0.71 | KIF11 (0.45) | — | |
| SCHEMBL5043804 | 0.71 | ALDH1A1 (0.42) | SMN1; SMN2POLBOPRM1DRD3DRD2 | |
| SCHEMBL9409974 | 0.69 | KIF11 (0.49) | — | |
| SCHEMBL361027 | 0.68 | ALOX5 (0.53) | SMN1; SMN2LMNAKDM4EALDH1A1CES1 | |
| SCHEMBL343793 | 0.67 | KMT2A (0.50) | SMN1; SMN2POLBOPRM1DRD3DRD2 | |
| SCHEMBL2761197 | 0.67 | MEN1 (0.39) | LMNACYP2C19CYP2C9CYP2D6 | |
| SCHEMBL17398530 | 0.67 | KIF11 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110809467-B | Modulators of SESTRIN-GATOR2 interactions and uses thereof | 纳维托制药有限公司 | 2023-03-10 | — | — | CN | disclosed |