Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 2/20 | 0.49 |
| ▸ | CHKA | P35790 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | AGXT | P21549 | 1/20 | 0.38 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL282701 | 0.93 | ADRA2C (0.50) | NCF1ADRA2CALDH1A1KDM4EGAA | |
| SCHEMBL3606736 | 0.88 | L3MBTL1 (0.37) | CHKALMNAALDH1A1KDM4EGAA | |
| SCHEMBL541280 | 0.84 | L3MBTL1 (0.41) | CHKALMNAALDH1A1KDM4EGAA | |
| SCHEMBL160644 | 0.82 | PRMT6 (0.42) | CHKALMNAALDH1A1KDM4EGAA | |
| SCHEMBL28339849 | 0.80 | ALDH1A1 (0.49) | ADRA2CALDH1A1KDM4EGAAMAPT | |
| SCHEMBL215829 | 0.79 | NCF1 (0.58) | NCF1CHKALMNAADRA2CALDH1A1 | |
| SCHEMBL1443053 | 0.78 | LMNA (0.47) | LMNAALDH1A1GAAMAPTKMT2A | |
| SCHEMBL9976438 | 0.78 | CHKA (0.61) | NCF1CHKALMNAADRA2CALDH1A1 | |
| SCHEMBL27581509 | 0.75 | DRD2 (0.65) | KDM4EGAA | |
| SCHEMBL4577581 | 0.75 | KDM4E (0.50) | ALDH1A1KDM4EMAPTGFERESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113135922-B | Azepane [4,3,2-cd ] isoindol-2-one derivatives and application thereof | 中国药科大学 | 2023-05-30 | — | — | CN | claimed |
| CN-113135922-B | Azepane [4,3,2-cd ] isoindol-2-one derivatives and application thereof | 中国药科大学 | 2023-05-30 | — | — | CN | disclosed |