Sugi Predict

Sugi Predict / Compounds / SCHEMBL2900752

SCHEMBL2900752

SCHEMBL2900752

Cc1cc(N)c(C(=O)O)cc1[N+](=O)[O-]

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 5/20 0.51
▸ TDP1 Q9NUW8 4/20 0.51
▸ ALDH1A1 P00352 3/20 0.51
▸ CYP3A4 P08684 3/20 0.51
▸ ALOX15 P16050 1/20 0.51
▸ LMNA P02545 2/20 0.47
▸ RECQL P46063 1/20 0.47
▸ L3MBTL1 Q9Y468 1/20 0.44
▸ CES2 O00748 1/20 0.43
▸ CES1 P23141 1/20 0.43
▸ DTYMK P23919 1/20 0.42
▸ GAA P10253 1/20 0.42
▸ KDM4E B2RXH2 2/20 0.41
▸ MEN1 O00255 2/20 0.41
▸ KMT2A Q03164 2/20 0.41
▸ IDO1 P14902 1/20 0.41
▸ MAPK1 P28482 2/20 0.40
▸ NPC1 O15118 1/20 0.40
▸ MAPT P10636 1/20 0.40
▸ RAB9A P51151 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31558212 1.00 TSHR (0.51) TSHRTDP1ALDH1A1CYP3A4ALOX15
SCHEMBL1964637 0.86 LMNA (0.56) TSHRTDP1ALDH1A1CYP3A4ALOX15
SCHEMBL8136865 0.85 TSHR (0.58) TSHRTDP1ALDH1A1CYP3A4LMNA
SCHEMBL8129334 0.85 TSHR (0.58) TSHRTDP1ALDH1A1CYP3A4LMNA
SCHEMBL2826498 0.84 TDP1 (0.56) TSHRTDP1ALDH1A1CYP3A4ALOX15
SCHEMBL9377747 0.84 TDP1 (0.56) TSHRTDP1ALDH1A1CYP3A4ALOX15
SCHEMBL4180430 0.84 TSHR (0.61) TSHRTDP1ALDH1A1CYP3A4LMNA
Hydrochloric Acid SCHEMBL11774750 0.82 TSHR (0.59) TSHRTDP1ALDH1A1CYP3A4LMNA
SCHEMBL3615613 0.82 PDGFRB (0.55) TSHRTDP1ALDH1A1CYP3A4ALOX15
SCHEMBL4374393 0.81 ALDH1A1 (0.53) TSHRTDP1ALDH1A1CYP3A4ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025101598-A1 BI-CYCLIC PYRIMIDINE COMPOUNDS, METHODS AND USES THEREOF ZENO MANAGEMENT, INC. (US) 2025-05-15 — — WO disclosed
US-11919905-B2 Substituted benzo[f]imidazo[1,2-a][1,4]diazepines as anesthetics Hangzhou Adamerck Pharmlabs, Inc. (CN) 2024-03-05 — — US disclosed
EP-3730495-B1 PYRIDYL IMIDAZOBENZODIAZEPINE PROPIONATE COMPOUND AND SYNTHESIS AND USE THEREOF HANGZHOU ADAMERCK PHARMLABS INC (CN) 2024-02-07 — — EP disclosed
CN-111727190-B Pyridylimidazole benzodiazepine Zhuo Bingsuan ester compound and synthesis and application thereof 杭州奥默医药股份有限公司 2023-10-27 — — CN disclosed
US-20220372037-A1 PYRIDYL IMIDAZOBENZODIAZEPINE PROPIONATE COMPOUND AND SYNTHESIS AND USE THEREOF Hangzhou Adamerck Pharmlabs Inc. (CN) 2022-11-24 — — US disclosed
US-20220348558-A1 INHIBITORS OF ENCEPHALITIC ALPHAVIRUSES UT RESEARCH FOUNDATION 2022-11-03 — — US disclosed
WO-2021046315-A2 INHIBITORS OF ENCEPHALITIC ALPHAVIRUSES WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2021-03-11 — — WO disclosed
CN-108033964-B Pyridyl imidazobenzodiazepine propionate compound and synthesis and application thereof 杭州奥默医药股份有限公司 2021-02-09 — — CN disclosed
EP-3730495-A1 PYRIDYL IMIDAZOBENZODIAZEPINE PROPIONATE COMPOUND AND SYNTHESIS AND USE THEREOF Hangzhou Adamerck Pharmlabs Inc. (CN) 2020-10-28 — — EP disclosed
CN-111727190-A Pyridyl imidazobenzodiazepine propionate compound and synthesis and application thereof 杭州奥默医药股份有限公司 2020-09-29 — — CN disclosed
CN-108033964-A A kind of Pyridinylimidazoles and benzodiazepine propionate compound and its synthesis and application 杭州奥默医药股份有限公司 2018-05-15 — — CN disclosed
EP-2240178-A1 PROLYL HYDROXYLASE INHIBITORS GlaxoSmithKline LLC (US) 2010-10-20 — — EP disclosed
US-20100004292-A1 Iminooxazolidine Derivatives and Their Use BAYER HEALTHCARE AG (DE) 2010-01-07 — — US disclosed
WO-2009086044-A1 PROLYL HYDROXYLASE INHIBITORS SMITH KLINE BEECHAM CORPORATION (US) 2009-07-09 — — WO disclosed
EP-1928868-A1 IMINOOXAZOLIDINE DERIVATIVES AND USE THEREOF Bayer HealthCare AG (DE) 2008-06-11 — — EP disclosed
WO-2007028520-A1 IMINOOXAZOLIDINE DERIVATIVES AND USE THEREOF BAYER HEALTHCARE AG (DE) 2007-03-15 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220348558-A1 INHIBITORS OF ENCEPHALITIC ALPHAVIRUSES NEFM, EIF2AK2, PMP22 TSHR 4860/4885TDP1 3643/4885ALDH1A1 1861/4885
US-11919905-B2 Substituted benzo[f]imidazo[1,2-a][1,4]diazepines as anesthetics GABRA1, GABRA4, GABRA6 TSHR 296/4885TDP1 791/4885ALDH1A1 430/4885
US-20100004292-A1 Iminooxazolidine Derivatives and Their Use PPOX, XDH, PNPO TSHR 3274/4885TDP1 849/4885ALDH1A1 906/4885
US-20220372037-A1 PYRIDYL IMIDAZOBENZODIAZEPINE PROPIONATE COMPOUND AND SYNTHESIS AND USE THEREOF GABBR1, GABRA1, GABRA6 TSHR 236/4885TDP1 1043/4885ALDH1A1 830/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.