SCHEMBL2901675

SCHEMBL2901675

Cc1cc(I)cc(C(=O)NC2(C3CC3)CC2)c1N

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
CRBN Q96SW2 1/20 0.32
P2RX7 Q99572 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13208800 0.88 CRBN (0.38) KDM4ECRBNP2RX7
SCHEMBL2901669 0.85 CSNK1E (0.32) P2RX7
SCHEMBL2901211 0.81 CXCR5 (0.35) KDM4ECRBN
SCHEMBL4619915 0.78 ALDH1A1 (0.39) P2RX7
SCHEMBL10280535 0.75 KDM4E (0.33) KDM4E
SCHEMBL3664060 0.74 KDM4E (0.42) KDM4E
SCHEMBL1314957 0.70 KDM4E (0.39) KDM4E
SCHEMBL317253 0.70 POLB (0.41) KDM4E
SCHEMBL857080 0.68 KDM4E (0.66) KDM4E
SCHEMBL4605842 0.68 KDM4E (0.46) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1871760-B1 CYANO ANTHRANILAMIDE INSECTICIDES SYNGENTA PARTICIPATIONS AG (CH) 2010-08-11 EP disclosed
US-7601743-B2 Cyano anthranilamide insecticides SYNGENTA CROP PROTECTION, INC. (US) 2009-10-13 US disclosed
US-20080182750-A1 Cyano Anthranilamide Insecticides SYNGENTA CROP PROTECTION, INC. (US) 2008-07-31 US disclosed
EP-1871760-A1 CYANO ANTHRANILAMIDE INSECTICIDES Syngeta Participations AG (CH) 2008-01-02 EP disclosed
WO-2006111341-A1 CYANO ANTHRANILAMIDE INSECTICIDES SYNGENTA PARTICIPATIONS AG (CH) 2006-10-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080182750-A1 Cyano Anthranilamide Insecticides CRY1, CRYAA, ALDH7A1 KDM4E 2291/4885CRBN 2289/4885P2RX7 3470/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.