SCHEMBL2905901

SCHEMBL2905901

Cc1cc(C#N)cc(C(=O)NC2(C3CC3)CC2)c1C(N)=O

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CXCR5 P32302 3/20 0.34
FASN P49327 3/20 0.34
CSNK1E P49674 1/20 0.31
MAP2K1 Q02750 1/20 0.31
RORC P51449 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2901211 0.86 CXCR5 (0.35) CXCR5FASNMAP2K1
SCHEMBL2901669 0.82 CSNK1E (0.32) CSNK1E
SCHEMBL3140934 0.77 EGLN1 (0.35) FASN
SCHEMBL2695321 0.75 EGLN1 (0.41)
SCHEMBL2780136 0.74 IRAK4 (0.41) MAP2K1
SCHEMBL2905905 0.72 HSD11B1 (0.35) FASNRORC
SCHEMBL21937817 0.72 POLB (0.44)
SCHEMBL2780137 0.68 ALDH1A1 (0.40)
SCHEMBL2901675 0.67 KDM4E (0.33)
SCHEMBL7011993 0.65 POLB (0.46) RORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1871760-B1 CYANO ANTHRANILAMIDE INSECTICIDES SYNGENTA PARTICIPATIONS AG (CH) 2010-08-11 EP disclosed
US-7601743-B2 Cyano anthranilamide insecticides SYNGENTA CROP PROTECTION, INC. (US) 2009-10-13 US disclosed
US-20080182750-A1 Cyano Anthranilamide Insecticides SYNGENTA CROP PROTECTION, INC. (US) 2008-07-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080182750-A1 Cyano Anthranilamide Insecticides CRY1, CRYAA, ALDH7A1 CXCR5 4676/4885FASN 845/4885CSNK1E 752/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.