Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR5 | P32302 | 3/20 | 0.35 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 6/20 | 0.31 |
| ▸ | FASN | P49327 | 3/20 | 0.31 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.31 |
| ▸ | VCP | P55072 | 1/20 | 0.31 |
| ▸ | USP14 | P54578 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2905901 | 0.86 | CXCR5 (0.34) | CXCR5MAP2K1FASN | |
| SCHEMBL2901675 | 0.81 | KDM4E (0.33) | KDM4ECRBN | |
| SCHEMBL31431870 | 0.78 | KDM1A (0.43) | KDM4E | |
| SCHEMBL635493 | 0.76 | KDM4E (0.39) | FASNVCPKDM4E | |
| SCHEMBL4619915 | 0.76 | ALDH1A1 (0.39) | CXCR5 | |
| SCHEMBL31431458 | 0.75 | KDM1A (0.42) | MAP2K1KDM4E | |
| SCHEMBL2695326 | 0.74 | EGLN1 (0.42) | — | |
| SCHEMBL31431699 | 0.72 | ALOX5 (0.43) | KDM4E | |
| SCHEMBL28057063 | 0.72 | HSP90AB1 (0.43) | FASNKDM4E | |
| SCHEMBL951068 | 0.71 | KDM4E (0.59) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1871760-B1 | CYANO ANTHRANILAMIDE INSECTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-08-11 | — | — | EP | disclosed |
| US-7601743-B2 | Cyano anthranilamide insecticides | SYNGENTA CROP PROTECTION, INC. (US) | 2009-10-13 | — | — | US | disclosed |
| US-7601743-B2 | Cyano anthranilamide insecticides | SYNGENTA CROP PROTECTION, INC. (US) | 2009-10-13 | — | — | US | disclosed |
| US-7601743-B2 | Cyano anthranilamide insecticides | SYNGENTA CROP PROTECTION, INC. (US) | 2009-10-13 | — | — | US | disclosed |
| US-20080182750-A1 | Cyano Anthranilamide Insecticides | SYNGENTA CROP PROTECTION, INC. (US) | 2008-07-31 | — | — | US | disclosed |
| US-20080182750-A1 | Cyano Anthranilamide Insecticides | SYNGENTA CROP PROTECTION, INC. (US) | 2008-07-31 | — | — | US | disclosed |
| US-20080182750-A1 | Cyano Anthranilamide Insecticides | SYNGENTA CROP PROTECTION, INC. (US) | 2008-07-31 | — | — | US | disclosed |
| EP-1871760-A1 | CYANO ANTHRANILAMIDE INSECTICIDES | Syngeta Participations AG (CH) | 2008-01-02 | — | — | EP | disclosed |
| WO-2006111341-A1 | CYANO ANTHRANILAMIDE INSECTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2006-10-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080182750-A1 | Cyano Anthranilamide Insecticides | CRY1, CRYAA, ALDH7A1 | CXCR5 4676/4885MAP2K1 3525/4885BACE1 364/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.