Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | USP7 | Q93009 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | STAT1 | P42224 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29028803 | 0.84 | ALDH1A1 (0.41) | MEN1KMT2AMAPTLMNAPDE10A | |
| SCHEMBL29028787 | 0.83 | MAPT (0.46) | MEN1KMT2AMAPTLMNAMPO | |
| SCHEMBL29028732 | 0.83 | MPO (0.45) | MEN1KMT2AMAPTLMNAPDE10A | |
| SCHEMBL29028700 | 0.83 | MPO (0.47) | MEN1KMT2AMAPTLMNAMPO | |
| SCHEMBL29028782 | 0.83 | LMNA (0.51) | KMT2AMAPTLMNAMPONPSR1 | |
| SCHEMBL29028690 | 0.76 | MAPT (0.39) | MAPTPDE10AKDM4EGAARXFP1 | |
| SCHEMBL29028696 | 0.76 | CSNK2A1 (0.40) | KMT2AMAPTPDE10AMPOKDM4E | |
| SCHEMBL29028699 | 0.76 | MEN1 (0.39) | MEN1KMT2AMAPTMPOKDM4E | |
| SCHEMBL29028776 | 0.75 | MPO (0.42) | LMNAPDE10AMPOGABRA1GABRG2 | |
| SCHEMBL29028717 | 0.75 | NPC1 (0.47) | MEN1KMT2AMAPTLMNAMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116332851-A | Cyanomethyl phenyl indazole compound and preparation method thereof | 河南中医药大学 | 2023-06-27 | — | — | CN | disclosed |