Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | BCAT1 | P54687 | 2/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | NEK2 | P51955 | 1/20 | 0.36 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | MAT2A | P31153 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29028803 | 0.89 | ALDH1A1 (0.41) | MEN1KMT2ASMN1; SMN2MAPTBCAT1 | |
| SCHEMBL29028690 | 0.84 | MAPT (0.39) | MAPTBCAT1CHEK1AURKACSNK1A1 | |
| SCHEMBL29028696 | 0.84 | CSNK2A1 (0.40) | KMT2ASMN1; SMN2MAPTBCAT1CA12 | |
| SCHEMBL29028724 | 0.83 | SMN1; SMN2 (0.46) | MEN1KMT2ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL29028700 | 0.83 | MPO (0.47) | MEN1KMT2ASMN1; SMN2MAPTBCAT1 | |
| SCHEMBL30473333 | 0.83 | MPO (0.55) | SMN1; SMN2MAPTFGFR1KDM4EMPO | |
| SCHEMBL29028711 | 0.83 | MPO (0.55) | SMN1; SMN2MAPTFGFR1KDM4EMPO | |
| SCHEMBL29028776 | 0.81 | MPO (0.42) | SMN1; SMN2FGFR1DYRK1AKDM4ENPC1 | |
| SCHEMBL29028704 | 0.76 | MEN1 (0.45) | MEN1KMT2ASMN1; SMN2MAPTFGFR1 | |
| SCHEMBL29028680 | 0.72 | NPC1 (0.43) | MEN1KMT2ASMN1; SMN2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116332851-A | Cyanomethyl phenyl indazole compound and preparation method thereof | 河南中医药大学 | 2023-06-27 | — | — | CN | disclosed |