Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HBB | P68871 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29028732 | 0.90 | MPO (0.45) | MPOFGFR1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL29028706 | 0.85 | MPO (0.47) | MPOFGFR1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL29028781 | 0.85 | MPO (0.47) | MPOALDH1A1SMN1; SMN2LMNANPC1 | |
| SCHEMBL1921521 | 0.82 | ALDH1A1 (0.44) | MPOFGFR1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL29028696 | 0.81 | CSNK2A1 (0.40) | MPOALDH1A1SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL29028690 | 0.81 | MAPT (0.39) | ALDH1A1KDM4ENPC1RAB9ATSHR | |
| SCHEMBL29028699 | 0.81 | MEN1 (0.39) | MPOFGFR1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL29028700 | 0.80 | MPO (0.47) | MPOALDH1A1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL29028704 | 0.75 | MEN1 (0.45) | MPOFGFR1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL29028803 | 0.73 | ALDH1A1 (0.41) | MPOALDH1A1SMN1; SMN2KDM4EGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116332851-A | Cyanomethyl phenyl indazole compound and preparation method thereof | 河南中医药大学 | 2023-06-27 | — | — | CN | disclosed |