Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | USP7 | Q93009 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29028781 | 0.87 | MPO (0.47) | MPOSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL29028732 | 0.85 | MPO (0.45) | MPOSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL29028776 | 0.85 | MPO (0.42) | MPOSMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL29028782 | 0.85 | LMNA (0.51) | MPOKMT2AHTTMAPTADORA3 | |
| SCHEMBL29028700 | 0.82 | MPO (0.47) | MPOSMN1; SMN2MEN1KMT2AHTT | |
| SCHEMBL30473333 | 0.82 | MPO (0.55) | MPOSMN1; SMN2HTTMAPTFGFR1 | |
| SCHEMBL29028720 | 0.82 | ADORA3 (0.40) | MPOHTTMAPTADORA3ADORA2A | |
| SCHEMBL29028711 | 0.82 | MPO (0.55) | MPOSMN1; SMN2HTTMAPTFGFR1 | |
| SCHEMBL29028769 | 0.82 | GRM5 (0.41) | MPOHTTMAPTADORA2AALDH1A1 | |
| SCHEMBL30473327 | 0.82 | MEN1 (0.41) | MPOMEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116332851-A | Cyanomethyl phenyl indazole compound and preparation method thereof | 河南中医药大学 | 2023-06-27 | — | — | CN | disclosed |