Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL862053 | 0.88 | CA2 (0.52) | TSHRTP53CA2CA1LMNA | |
| SCHEMBL29790333 | 0.88 | CA2 (0.52) | TSHRTP53CA2CA1LMNA | |
| Catechol SCHEMBL9641287 | 0.86 | CA2 (0.50) | TSHRTP53CA2CA1LMNA | |
| SCHEMBL337282 | 0.86 | CA2 (0.50) | TSHRTP53CA2CA1LMNA | |
| Ammonia Solution, Strong SCHEMBL9187024 | 0.86 | CA2 (0.50) | TSHRTP53CA2CA1LMNA | |
| SCHEMBL28598792 | 0.79 | ALDH1A1 (0.45) | TSHRLMNAMAPTGAAALDH1A1 | |
| SCHEMBL30586460 | 0.79 | ENPP2 (0.34) | KDM4EENPP2ORAI1ORAI2ORAI3 | |
| SCHEMBL30426584 | 0.79 | HTR7 (0.36) | LMNAMAPTGAAALDH1A1HPGD | |
| SCHEMBL29177121 | 0.79 | CA3 (0.34) | ORAI1ORAI2ORAI3MEN1KMT2A | |
| SCHEMBL29220692 | 0.78 | RXRA (0.38) | HSD11B1ATMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111909217-B | Bis (di-tert-butyl-4-dimethylaminophenylphosphine) tetrabromodipalladium (II) compound and preparation method and application thereof | 昆明贵金属研究所 | 2023-05-02 | — | — | CN | disclosed |