Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.81 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.80 |
| ▸ | HPGD | P15428 | 5/20 | 0.80 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.80 |
| ▸ | DRD1 | P21728 | 4/20 | 0.58 |
| ▸ | HTR2C | P28335 | 3/20 | 0.58 |
| ▸ | PTPRCAP | Q14761 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | DRD5 | P21918 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23949488 | 0.90 | DRD2 (1.00) | DRD2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL563496 | 0.90 | DRD2 (1.00) | DRD2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9976810 | 0.88 | DRD2 (0.63) | DRD2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL30029891 | 0.87 | HTR2C (0.77) | DRD2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL29506718 | 0.87 | HTR2C (0.77) | DRD2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL27850407 | 0.85 | ALDH1A1 (0.69) | DRD2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL11055620 | 0.85 | ALDH1A1 (0.69) | DRD2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL29398835 | 0.85 | ALDH1A1 (0.69) | DRD2KDM4EALDH1A1HPGDHSD17B10 | |
| Norcorydine SCHEMBL31504460 | 0.82 | DRD2 (0.69) | DRD2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL31029778 | 0.81 | KDM4E (0.70) | DRD2KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116478941-A | CYP80G protein and application of encoding gene thereof in catalysis of synthesis of lotus leaf aporphine alkaloids | 中国中医科学院中药研究所 | 2023-07-25 | — | — | CN | disclosed |