Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | PARP1 | P09874 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 4/20 | 0.49 |
| ▸ | MAOA | P21397 | 3/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.45 |
| ▸ | FEN1 | P39748 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2904740 | 1.00 | ALDH1A1 (0.54) | ALDH1A1GAAMAPTHPGDHTT | |
| Chlorobenzene SCHEMBL28198788 | 0.83 | MAOB (0.51) | ALDH1A1GAAMAPTHTTMAOB | |
| SCHEMBL27757879 | 0.82 | MAOB (0.49) | MAPTHPGDHTTPARP1MAOB | |
| SCHEMBL31167601 | 0.80 | ALDH1A1 (0.71) | ALDH1A1GAAMAPTHPGDHTT | |
| SCHEMBL9122850 | 0.79 | CA12 (0.53) | ALDH1A1GAAMAPTPARP1KDM4E | |
| SCHEMBL9122855 | 0.79 | CA12 (0.53) | ALDH1A1GAAMAPTPARP1KDM4E | |
| SCHEMBL3045995 | 0.79 | ALDH1A1 (0.59) | ALDH1A1GAAMAPTHPGDHTT | |
| SCHEMBL4074756 | 0.78 | CES2 (0.57) | MAPTHPGDHTTPARP1CYP1A2 | |
| SCHEMBL22715128 | 0.78 | PARP1 (0.53) | ALDH1A1GAAMAPTHPGDHTT | |
| SCHEMBL22715126 | 0.78 | PARP1 (0.53) | ALDH1A1GAAMAPTHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2035573-B1 | METHODS FOR IDENTIFYING MODULATORS OF EOXIN FORMATION | BIOLIPOX AB (SE) | 2010-08-18 | — | — | EP | disclosed |
| US-20090247634-A1 | Methods for identifying modulators of eoxin formation | CLAESSON HANS-ERIK | 2009-10-01 | — | — | US | disclosed |
| EP-2035573-A1 | METHODS FOR IDENTIFYING MODULATORS OF EOXIN FORMATION | Biolipox AB (SE) | 2009-03-18 | — | — | EP | disclosed |
| US-20080227787-A1 | Use of New Lipoxygenase Inhibitors | BIOLIPOX AB (SE) | 2008-09-18 | — | — | US | disclosed |
| WO-2008001079-A1 | METHODS FOR IDENTIFYING MODULATORS OF EOXIN FORMATION | BIOLIPOX AB (SE) | 2008-01-03 | — | — | WO | disclosed |
| EP-1725227-A1 | USE OF NEW LIPOXYGENASE INHIBITORS | Biolipox AB (SE) | 2006-11-29 | — | — | EP | disclosed |
| WO-2005084656-A1 | USE OF NEW LIPOXYGENASE INHIBITORS | BIOLIPOX AB (SE) | 2005-09-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247634-A1 | Methods for identifying modulators of eoxin formation | LTA4H, LTC4S, LTB4R2 | ALDH1A1 3239/4885GAA 4108/4885MAPT 3855/4885 |
| US-20080227787-A1 | Use of New Lipoxygenase Inhibitors | ALOX15, ALOX15B, ALOX12 | ALDH1A1 464/4885GAA 2082/4885MAPT 4603/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.