Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 5/20 | 0.48 |
| ▸ | FABP4 | P15090 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7833897 | 0.88 | MAPT (0.62) | NPC1RAB9AMAPTALOX15GAA | |
| SCHEMBL27727061 | 0.83 | MAPT (0.47) | NPC1RAB9AMAPTALOX15GAA | |
| SCHEMBL4249837 | 0.81 | FABP4 (0.71) | NPC1RAB9AMAPTALOX15GAA | |
| SCHEMBL8052123 | 0.81 | MEN1 (0.58) | NPC1RAB9AMAPTALOX15GAA | |
| SCHEMBL15688476 | 0.80 | SIRT2 (0.71) | NPC1RAB9AMAPTGAATDP1 | |
| SCHEMBL28658698 | 0.79 | MAPT (0.78) | NPC1RAB9AMAPTALOX15GAA | |
| SCHEMBL29050684 | 0.78 | NPC1 (0.59) | NPC1RAB9AMAPTTDP1MEN1 | |
| SCHEMBL605325 | 0.75 | KDM4E (0.58) | NPC1RAB9AMAPTGAAFABP4 | |
| SCHEMBL7959032 | 0.75 | ALDH1A1 (0.45) | NPC1RAB9AMAPTGAAKMT2A | |
| SCHEMBL12112435 | 0.75 | MAPT (0.58) | MAPTALOX15SIRT2FABP4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116589406-A | Preparation method of polysubstituted acridine derivative | 深圳职业技术学院 | 2023-08-15 | — | — | CN | disclosed |