SCHEMBL290510

SCHEMBL290510

CCCCNCCC(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 1/20 0.54
GPR84 Q9NQS5 7/20 0.52
PPARG P37231 7/20 0.52
PPARD Q03181 7/20 0.52
PPARA Q07869 7/20 0.52
TSHR P16473 6/20 0.52
HDAC11 Q96DB2 5/20 0.52
PTPN1 P18031 3/20 0.52
ALDH1A1 P00352 3/20 0.52
TLR2 O60603 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
FABP4 P15090 2/20 0.52
ALOX15 P16050 2/20 0.52
KMT2A Q03164 2/20 0.52
SLC22A6 Q4U2R8 1/20 0.52
SLC22A8 Q8TCC7 1/20 0.52
MEN1 O00255 1/20 0.52
ESR1 P03372 1/20 0.52
PDE4A P27815 1/20 0.52
PDE3A Q14432 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31274732 0.98 AKR1B1 (0.52) AKR1B1GPR84PPARGPPARDPPARA
SCHEMBL31688839 0.96 GPR84 (0.54) AKR1B1GPR84PPARGPPARDPPARA
SCHEMBL30064496 0.96 GPR84 (0.54) AKR1B1GPR84PPARGPPARDPPARA
SCHEMBL674092 0.93 TSHR (0.59) AKR1B1GPR84PPARGPPARDPPARA
SCHEMBL19798143 0.91 GPR84 (0.60) AKR1B1GPR84PPARGPPARDPPARA
SCHEMBL148702 0.91 GPR84 (0.60) AKR1B1GPR84PPARGPPARDPPARA
SCHEMBL7954863 0.91 GPR84 (0.60) AKR1B1GPR84PPARGPPARDPPARA
SCHEMBL20138612 0.91 GPR84 (0.60) AKR1B1GPR84PPARGPPARDPPARA
SCHEMBL16147341 0.91 TSHR (0.56) AKR1B1GPR84PPARGPPARDPPARA
SCHEMBL8437709 0.91 GPR84 (0.60) AKR1B1GPR84PPARGPPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108289810-A Composition comprising a hydroxylated diphenylmethane derivative 莱雅公司 2018-07-17 CN claimed
US-7364720-B2 Photostabilization of dibenzoylmethane UV-screening agents with arylalkyl benzoate compounds/amide-based oils and photoprotective compositions comprised thereof L'OREAL (FR) 2008-04-29 US claimed
US-7357920-B2 Photostable photoprotective compositions comprising dibenzoylmethane and amide oil compounds and a compound that accepts the excited triplet level energy of said dibenzoylmethane(s) L'OREAL (FR) 2008-04-15 US claimed
EP-1064254-B1 ALIPHATIC AMINO CARBOXYLIC AND AMINO PHOSPHONIC ACIDS, AMINO NITRILES AND AMINO TETRAZOLES AS CELLULAR RESCUE AGENTS UNIV SASKATCHEWAN (CA) 2007-10-17 EP claimed
US-20060083698-A1 Photostable photoprotective compositions comprising dibenzoylmethane and amide oil compounds and a compound that accepts the excited triplet level energy of said dibenzoylmethane(s) L'OREAL (FR) 2006-04-20 US claimed
US-20060002873-A1 Photostabilization of dibenzoylmethane UV-screening agents with arylalkyl benzoate compounds/amide-based oils and photoprotective compositions comprised thereof L'OREAL (FR) 2006-01-05 US claimed
US-6872401-B2 Cosmetic/dermatological compositions comprising a tetrahydrocurcuminoid and an amide oil L'OREAL (FR) 2005-03-29 US claimed
US-20040009200-A1 Cosmetic/dermatological compositions comprising a tetrahydrocurcuminoid and an amide oil SOCIETE L'OREAL S.A. (FR) 2004-01-15 US claimed
JP-2002507591-A 2002-03-12 JP claimed
EP-1064254-A2 ALIPHATIC AMINO CARBOXYLIC AND AMINO PHOSPHONIC ACIDS, AMINO NITRILES AND AMINO TETRAZOLES AS CELLULAR RESCUE AGENTS University of Saskatchewan Technologies Inc. (CA) 2001-01-03 EP claimed
WO-1999048858-A2 ALIPHATIC AMINO CARBOXYLIC AND AMINO PHOSPHONIC ACIDS, AMINO NITRILES AND AMINO TETRAZOLES AS CELLULAR RESCUE AGENTS UNIVERSITY OF SASKATCHEWAN TECHNOLOGIES INC. (CA) 1999-09-30 WO claimed
CN-117338637-A Compositions comprising hydroxylated diphenylmethane derivatives 莱雅公司 2024-01-05 CN disclosed
EP-3407865-B1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE AND AN OILY PHASE COMPRISING AT LEAST ONE N-SUBSTITUTED AMIDE OREAL (FR) 2023-10-18 EP disclosed
CN-112759676-B Solid catalyst component for preparing polyolefin, catalyst and application thereof 中国石油化工股份有限公司 2023-08-15 CN disclosed
US-11534419-B2 N-acetyl beta alanine methods of use THERMOLIFE INTERNATIONAL, LLC (US) 2022-12-27 US disclosed
EP-0276872-B1 ELECTRODEPOSITION COATING COMPOSITION CONTAINING A MODIFIED EPOXY RESIN HAVING CHARGEABLE GROUPS Nippon Paint Co., Ltd. (JP) 1992-12-30 EP disclosed
US-4927814-A Diphosphonate derivatives, pharmaceutical compositions and methods of use BOEHRINGER MANNHEIM GMBH (DE) 1990-05-22 US disclosed
US-4829105-A GRAFT POLYMERS, ANIONIC, HYDROPHILIC NIPPON PAINT CO., LTD. (JP) 1989-05-09 US disclosed
US-4217238-A BASIC SALT, SCRUBBING EXXON RESEARCH & ENGINEERING CO. (US) 1980-08-12 US disclosed
US-4094957-A CARBON DIOXIDE EXXON RESEARCH & ENGINEERING CO. (US) 1978-06-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060083698-A1 Photostable photoprotective compositions comprising dibenzoylmethane and amide oil compounds and a compound that accepts the excited triplet level energy of said dibenzoylmethane(s) NOTUM, CUTA, WEE1 AKR1B1 2464/4885GPR84 2939/4885PPARG 41/4885
US-20060002873-A1 Photostabilization of dibenzoylmethane UV-screening agents with arylalkyl benzoate compounds/amide-based oils and photoprotective compositions comprised thereof ARNT, AHR, CRYZ AKR1B1 2357/4885GPR84 1194/4885PPARG 15/4885
US-20040009200-A1 Cosmetic/dermatological compositions comprising a tetrahydrocurcuminoid and an amide oil KRT18, DHCR24, FABP4 AKR1B1 87/4885GPR84 2894/4885PPARG 96/4885
US-11534419-B2 N-acetyl beta alanine methods of use AADAT, B3GNT2, AANAT AKR1B1 1342/4885GPR84 3935/4885PPARG 2393/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.