Sugi Predict

Sugi Predict / Compounds / SCHEMBL2908276

SCHEMBL2908276

SCHEMBL2908276

CS(=O)(=O)c1ccc(N)c(S(C)(=O)=O)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ G6PD P11413 1/20 0.60
▸ IDE P14735 1/20 0.60
▸ SMN1; SMN2 Q16637 1/20 0.55
▸ L3MBTL1 Q9Y468 1/20 0.44
▸ ENPP2 Q13822 1/20 0.41
▸ PHLPP2 Q6ZVD8 1/20 0.41
▸ CA12 O43570 4/20 0.41
▸ CA1 P00915 4/20 0.41
▸ CA2 P00918 4/20 0.41
▸ CA4 P22748 4/20 0.41
▸ CA6 P23280 4/20 0.41
▸ CA5A P35218 4/20 0.41
▸ CA7 P43166 4/20 0.41
▸ CA9 Q16790 4/20 0.41
▸ CA14 Q9ULX7 4/20 0.41
▸ CA5B Q9Y2D0 4/20 0.41
▸ PKM P14618 2/20 0.39
▸ KDM4E B2RXH2 1/20 0.39
▸ MEN1 O00255 1/20 0.39
▸ GAA P10253 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5353740 0.88 G6PD (0.56) G6PDIDESMN1; SMN2L3MBTL1CA12
SCHEMBL9815491 0.86 G6PD (0.46) G6PDIDESMN1; SMN2L3MBTL1PHLPP2
SCHEMBL343565 0.86 G6PD (0.55) G6PDIDESMN1; SMN2ENPP2PHLPP2
SCHEMBL9815495 0.84 ALDH1A1 (0.52) G6PDIDESMN1; SMN2L3MBTL1PHLPP2
SCHEMBL898422 0.82 G6PD (0.64) G6PDIDESMN1; SMN2ENPP2CA12
SCHEMBL6932811 0.81 G6PD (0.58) G6PDIDEENPP2PHLPP2CA12
SCHEMBL9175606 0.80 L3MBTL1 (0.61) G6PDIDEL3MBTL1CA12CA1
SCHEMBL11685666 0.80 ALDH1A1 (0.51) G6PDIDESMN1; SMN2CA12CA1
SCHEMBL30908409 0.78 CYP3A4 (0.50) G6PDIDESMN1; SMN2L3MBTL1CA12
SCHEMBL20150187 0.78 CYP3A4 (0.50) G6PDIDESMN1; SMN2L3MBTL1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025215201-A1 PANNEXIN-1 INHIBITORS AND USES THEREOF PANNTHERAPI (FR) 2025-10-16 — — WO disclosed
US-9493480-B2 Monomeric trioxane amide sulfur compounds THE JOHNS HOPKINS UNIVERSITY (US) 2016-11-15 — — US disclosed
US-20150183798-A1 MONOMERIC TRIOXANE AMIDE SULFUR COMPOUNDS THE JOHNS HOPKINS UNIVERSITY (US) 2015-07-02 — — US disclosed
EP-1325920-B1 N-SUBSTITUTED BENZOTHIOPHENESULFONAMIDE DERIVATIVES TOA EIYO LTD (JP) 2010-08-25 — — EP disclosed
US-7700655-B2 Antiallergic agents INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) 2010-04-20 — — US disclosed
US-7399781-B2 N-substituted benzothiophenesulfonamide derivatives TOA EIYO LTD. (JP) 2008-07-15 — — US disclosed
US-20080090779-A1 ANTIALLERGIC AGENTS INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) 2008-04-17 — — US disclosed
US-20070185059-A1 Antiallergic agents INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) 2007-08-09 — — US disclosed
US-20070185110-A1 Antiallergic agents INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) 2007-08-09 — — US disclosed
US-7071220-B2 N-substituted benzothiophenesulfonamide derivatives TOA EIYO LTD. (JP) 2006-07-04 — — US disclosed
US-4358526-A MAGENTA AZO DYES; COLORFASTNESS FUJI PHOTO FILM CO., LTD. (JP) 1982-11-09 — — US disclosed
EP-0036081-A1 Azo dyestuffs as well as their preparation and their use in dyeing synthetic fibres BAYER AG (DE) 1981-09-23 — — EP disclosed
US-4217271-A Basic azo dyestuffs containing a n-picolinium alkylene amino phenyl group IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1980-08-12 — — US disclosed
US-4189428-A DYEABILITY, COLORFASTNESS, RESISTANCE TO SUBLIMATION, IMPROVED BRIGHTNESS EASTMAN KODAK COMPANY (US) 1980-02-19 — — US disclosed
US-4153413-A DYEING POLYESTER OR CELLULOSE TRIACETATE WITH A DISPERSE AZO DYESTUFF, HEAT TREATMENT, PADDING, PRINTING IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1979-05-08 — — US disclosed
US-4140683-A DISPERSE DYES FOR POLYESTERS EASTMAN KODAK COMPANY (US) 1979-02-20 — — US disclosed
US-4134723-A DYEING AROMATIC POLYESTER/POLYAMIDE OR AROMATIC POLYESTER/CELLULOSE BLENDS WITH DISPERSE MONOAZO DYE, ALKALINE BATH IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1979-01-16 — — US disclosed
US-4060544-A COUPLERS GAF CORPORATION (US) 1977-11-29 — — US disclosed
US-4049643-A DYES FOR POLYESTERS EASTMAN KODAK COMPANY (US) 1977-09-20 — — US disclosed
US-4039524-A Keto-amido containing phenylazo benzothiazole dyestuffs GAF CORPORATION (US) 1977-08-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080090779-A1 ANTIALLERGIC AGENTS NAT1, EPX, HRH2 G6PD 2078/4885IDE 3235/4885SMN1; SMN2 4693/4885
US-20070185110-A1 Antiallergic agents NAT1, EPX, AHR G6PD 2016/4885IDE 3099/4885SMN1; SMN2 4695/4885
US-20150183798-A1 MONOMERIC TRIOXANE AMIDE SULFUR COMPOUNDS AS3MT, SQOR, TST G6PD 51/4885IDE 4725/4885SMN1; SMN2 1555/4885
US-20070185059-A1 Antiallergic agents NAT1, EPX, AHR G6PD 2048/4885IDE 3201/4885SMN1; SMN2 4709/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.