SCHEMBL17912486

SCHEMBL17912486

Cc1oc2cc(Br)c(O)cc2c1C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.51
KMT2A Q03164 5/20 0.51
PRNP P04156 1/20 0.51
TSHR P16473 4/20 0.48
MAPK1 P28482 3/20 0.48
ALDH1A1 P00352 2/20 0.48
ALOX15 P16050 2/20 0.48
HSD17B10 Q99714 2/20 0.48
SLC26A4 O43511 2/20 0.46
BLM P54132 1/20 0.46
ATM Q13315 1/20 0.46
GPR35 Q9HC97 2/20 0.45
SMN1; SMN2 Q16637 3/20 0.44
LMNA P02545 2/20 0.44
HPGD P15428 1/20 0.44
RAB9A P51151 1/20 0.44
SLC22A12 Q96S37 1/20 0.44
CYP2C19 P33261 1/20 0.43
MAPT P10636 2/20 0.42
HTT P42858 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29104693 0.81 LMNA (0.46) MEN1KMT2AALDH1A1HSD17B10SLC26A4
SCHEMBL17912483 0.81 EYA3 (0.48) MEN1KMT2AALDH1A1SLC26A4BLM
SCHEMBL15019934 0.75 SLC26A4 (0.64) MEN1KMT2APRNPTSHRALDH1A1
SCHEMBL10938750 0.75 GPR35 (0.54) MEN1KMT2AMAPK1ALDH1A1ALOX15
SCHEMBL16654658 0.75 PTGS2 (0.47) MEN1KMT2AALDH1A1HSD17B10SLC26A4
Hydrochloric Acid SCHEMBL11133623 0.74 GPR35 (0.53) MEN1KMT2AMAPK1ALDH1A1ALOX15
SCHEMBL24470616 0.73 HTT (0.64) MEN1KMT2AALDH1A1HSD17B10SLC26A4
SCHEMBL29630216 0.73 HTT (0.64) MEN1KMT2AALDH1A1HSD17B10SLC26A4
SCHEMBL2083566 0.73 ALDH1A1 (0.54) TSHRALDH1A1ALOX15HSD17B10SMN1; SMN2
SCHEMBL18809255 0.73 MEN1 (0.56) MEN1KMT2APRNPMAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016111636-A1 BENZO[1,2-B:4,5-B]FURAN DERIVATIVES AS LIGANDS OF RUTHENIUM DYES AND METHODS FOR OBTAINING THEREOF SYNTHEX TECHNOLOGIES Sp. z o.o. (PL) 2016-07-14 WO claimed