Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29107248 | 0.88 | SIRT2 (0.40) | SIRT2SIRT1HDAC3HDAC4HDAC1 | |
| SCHEMBL29107254 | 0.87 | DRD2 (0.41) | DRD2DRD4HDAC6PPARGALDH1A1 | |
| SCHEMBL29107246 | 0.84 | SMN1; SMN2 (0.48) | DRD2DRD4HCRTR1HCRTR2PPARG | |
| SCHEMBL21803243 | 0.84 | GSK3B (0.44) | PPARGACHEGSK3BTP53 | |
| SCHEMBL29107250 | 0.82 | PPARG (0.41) | DRD2DRD4PPARGBCHETP53 | |
| Iodide SCHEMBL28993212 | 0.82 | GSK3B (0.43) | PPARGACHEGSK3BTP53 | |
| Bromide SCHEMBL28315346 | 0.82 | GSK3B (0.43) | PPARGACHEGSK3BTP53 | |
| SCHEMBL29107251 | 0.81 | PPARG (0.40) | HDAC3HDAC6PPARGGSK3BMAPT | |
| SCHEMBL27885890 | 0.81 | GSK3B (0.41) | PPARGACHEGSK3BTP53 | |
| SCHEMBL27708014 | 0.77 | MAOB (0.42) | DRD2DRD4SIRT2SIRT1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184558-A | Thiophenylamide compound, and preparation method and application thereof | 五邑大学 | 2024-06-14 | — | — | CN | disclosed |
| CN-117069742-A | Spiro [ pyridine-thiazolidine ] compound and preparation method and application thereof | 五邑大学 | 2023-11-17 | — | — | CN | disclosed |