Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 4/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMO | Q99835 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL28993212 | 0.98 | GSK3B (0.43) | GSK3BPPARGEHMT2BRD4LMNA | |
| SCHEMBL29107250 | 0.89 | PPARG (0.41) | PPARGTP53SMO | |
| SCHEMBL29107251 | 0.87 | PPARG (0.40) | GSK3BPPARGEHMT2BRD4LMNA | |
| SCHEMBL29107246 | 0.87 | SMN1; SMN2 (0.48) | PPARGMAPK1TP53SMN1; SMN2 | |
| SCHEMBL29107254 | 0.85 | DRD2 (0.41) | GSK3BPPARGLMNATP53SMN1; SMN2 | |
| SCHEMBL29107247 | 0.84 | CHRM5 (0.43) | GSK3BPPARGACHETP53 | |
| SCHEMBL16709169 | 0.82 | MAOA (0.38) | GSK3BPPARGSMN1; SMN2KDM1A | |
| SCHEMBL16709179 | 0.82 | MAOA (0.42) | GSK3BLMNATP53SMN1; SMN2KDM1A | |
| SCHEMBL29107249 | 0.81 | GSK3B (0.40) | GSK3BMAPK1TP53SMN1; SMN2NPC1 | |
| SCHEMBL30702419 | 0.80 | SMN1; SMN2 (0.38) | GSK3BPPARGSMN1; SMN2KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114874638-B | Meso-position substituted pentamethine cyanine dye, preparation method and application thereof, and fluorescent probe | 西安建筑科技大学 | 2024-01-19 | — | — | CN | claimed |
| CN-118184558-A | Thiophenylamide compound, and preparation method and application thereof | 五邑大学 | 2024-06-14 | — | — | CN | disclosed |
| CN-117069742-A | Spiro [ pyridine-thiazolidine ] compound and preparation method and application thereof | 五邑大学 | 2023-11-17 | — | — | CN | disclosed |
| US-10968386-B2 | Pentamethine cyanine dye and preparation method therefor | SHENZHEN UNIVERSITY (CN) | 2021-04-06 | — | — | US | disclosed |
| US-20200095499-A1 | PENTAMETHINE CYANINE DYE AND PREPARATION METHOD THEREFOR | SHENZHEN UNIVERSITY (CN) | 2020-03-26 | — | — | US | disclosed |
| CN-102627869-B | Preparation method of near-infrared heptamethine cyanine dye and use of the near-infrared heptamethine cyanine dye in weak polarity-polarity mixed solvent fluorescence spectrum test | JIANGNAN UNIVERSITY (CN) | 2014-10-22 | — | — | CN | disclosed |
| CN-102627869-A | Preparation method of near-infrared heptamethine cyanine dye and use of the near-infrared heptamethine cyanine dye in weak polarity-polarity mixed solvent fluorescence spectrum test | UNIV JIANGNAN | 2012-08-08 | — | — | CN | disclosed |
| CN-101256360-B | Radiosensitive resin composition, laminated insulation film and micro lens, preparation method thereof | JSR CORP | 2012-06-20 | — | — | CN | disclosed |