Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | SMO | Q99835 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 10/20 | 0.39 |
| ▸ | DRD2 | P14416 | 8/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21803243 | 0.89 | GSK3B (0.44) | PPARGSMOTP53 | |
| Iodide SCHEMBL28993212 | 0.87 | GSK3B (0.43) | PPARGSMOTP53 | |
| SCHEMBL29107246 | 0.86 | SMN1; SMN2 (0.48) | PPARGDRD4DRD2TP53 | |
| SCHEMBL29107251 | 0.86 | PPARG (0.40) | PPARGTP53 | |
| SCHEMBL29107254 | 0.84 | DRD2 (0.41) | PPARGDRD4DRD2TP53 | |
| SCHEMBL29107247 | 0.82 | CHRM5 (0.43) | PPARGDRD4DRD2TP53BCHE | |
| SCHEMBL29107245 | 0.78 | MEN1 (0.51) | PPARGTP53 | |
| SCHEMBL16709169 | 0.78 | MAOA (0.38) | PPARG | |
| SCHEMBL16709179 | 0.78 | MAOA (0.42) | DRD4DRD2ADRA1DADRA1ATP53 | |
| SCHEMBL29107249 | 0.77 | GSK3B (0.40) | TP53BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184558-A | Thiophenylamide compound, and preparation method and application thereof | 五邑大学 | 2024-06-14 | — | — | CN | disclosed |
| CN-117069742-A | Spiro [ pyridine-thiazolidine ] compound and preparation method and application thereof | 五邑大学 | 2023-11-17 | — | — | CN | disclosed |