Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 5/20 | 0.40 |
| ▸ | CETP | P11597 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29107247 | 0.88 | CHRM5 (0.43) | SIRT2SIRT1NPSR1TP53KDM4E | |
| SCHEMBL21803243 | 0.79 | GSK3B (0.44) | TP53SMN1; SMN2NPC1MAPK1RAB9A | |
| Iodide SCHEMBL28993212 | 0.78 | GSK3B (0.43) | TP53SMN1; SMN2NPC1MAPK1RAB9A | |
| Bromide SCHEMBL28315346 | 0.78 | GSK3B (0.43) | TP53SMN1; SMN2NPC1MAPK1RAB9A | |
| SCHEMBL29107254 | 0.78 | DRD2 (0.41) | NPSR1HSP90AA1HSP90AB1TP53HTT | |
| SCHEMBL29107246 | 0.77 | SMN1; SMN2 (0.48) | TP53SMN1; SMN2TSHRMAPK1MAPT | |
| SCHEMBL27885890 | 0.77 | GSK3B (0.41) | TP53SMN1; SMN2NPC1MAPK1RAB9A | |
| SCHEMBL29107249 | 0.77 | GSK3B (0.40) | NPSR1TP53KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL29107250 | 0.76 | PPARG (0.41) | TP53ADRA1A | |
| SCHEMBL29107251 | 0.74 | PPARG (0.40) | TP53SMN1; SMN2MAPK1MAPTHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117069742-A | Spiro [ pyridine-thiazolidine ] compound and preparation method and application thereof | 五邑大学 | 2023-11-17 | — | — | CN | disclosed |