Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21803243 | 0.87 | GSK3B (0.44) | PPARGGSK3BSMN1; SMN2TP53BRD4 | |
| SCHEMBL29107250 | 0.86 | PPARG (0.41) | PPARGTP53 | |
| Iodide SCHEMBL28993212 | 0.86 | GSK3B (0.43) | PPARGGSK3BSMN1; SMN2TP53BRD4 | |
| SCHEMBL29107246 | 0.85 | SMN1; SMN2 (0.48) | PPARGSMN1; SMN2TP53THRBMAPK1 | |
| SCHEMBL29107254 | 0.82 | DRD2 (0.41) | PPARGGSK3BSMN1; SMN2TP53HDAC6 | |
| SCHEMBL29107247 | 0.81 | CHRM5 (0.43) | PPARGGSK3BTP53HDAC3HDAC6 | |
| SCHEMBL29107245 | 0.77 | MEN1 (0.51) | PPARGGSK3BTP53HDAC3HDAC6 | |
| SCHEMBL16709169 | 0.77 | MAOA (0.38) | PPARGGSK3BSMN1; SMN2MEN1POLB | |
| SCHEMBL16709179 | 0.77 | MAOA (0.42) | GSK3BSMN1; SMN2TP53LMNAMEN1 | |
| SCHEMBL29107249 | 0.75 | GSK3B (0.40) | GSK3BSMN1; SMN2TP53THRBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184558-A | Thiophenylamide compound, and preparation method and application thereof | 五邑大学 | 2024-06-14 | — | — | CN | disclosed |
| CN-117069742-A | Spiro [ pyridine-thiazolidine ] compound and preparation method and application thereof | 五邑大学 | 2023-11-17 | — | — | CN | disclosed |