Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21803243 | 0.87 | GSK3B (0.44) | SMN1; SMN2TP53PPARGMAPK1 | |
| SCHEMBL29107250 | 0.86 | PPARG (0.41) | TP53PPARGDRD2DRD4 | |
| Iodide SCHEMBL28993212 | 0.86 | GSK3B (0.43) | SMN1; SMN2TP53PPARGMAPK1 | |
| SCHEMBL29107251 | 0.85 | PPARG (0.40) | SMN1; SMN2TP53THRBMAPTPPARG | |
| SCHEMBL29107247 | 0.84 | CHRM5 (0.43) | TP53ALDH1A1MAPTPPARGDRD2 | |
| SCHEMBL29107254 | 0.82 | DRD2 (0.41) | SMN1; SMN2TP53ALDH1A1MAPTPPARG | |
| SCHEMBL29107248 | 0.77 | SIRT2 (0.40) | SMN1; SMN2TP53TSHRMAPTMAPK1 | |
| SCHEMBL29107245 | 0.77 | MEN1 (0.51) | TP53TSHRALDH1A1MAPTPPARG | |
| SCHEMBL16709179 | 0.77 | MAOA (0.42) | SMN1; SMN2TP53TSHRALDH1A1MAPT | |
| SCHEMBL16709169 | 0.77 | MAOA (0.38) | SMN1; SMN2PPARGMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184558-A | Thiophenylamide compound, and preparation method and application thereof | 五邑大学 | 2024-06-14 | — | — | CN | disclosed |
| CN-117069742-A | Spiro [ pyridine-thiazolidine ] compound and preparation method and application thereof | 五邑大学 | 2023-11-17 | — | — | CN | disclosed |