Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29107247 | 0.87 | CHRM5 (0.43) | DRD2DRD4PPARGHTTTP53 | |
| SCHEMBL21803243 | 0.85 | GSK3B (0.44) | PPARGTP53LMNASMN1; SMN2GSK3B | |
| SCHEMBL29107250 | 0.84 | PPARG (0.41) | DRD2DRD4PPARGTP53 | |
| Iodide SCHEMBL28993212 | 0.83 | GSK3B (0.43) | PPARGTP53LMNASMN1; SMN2GSK3B | |
| SCHEMBL29107251 | 0.82 | PPARG (0.40) | PPARGTP53LMNAPOLBKMT2A | |
| SCHEMBL29107246 | 0.82 | SMN1; SMN2 (0.48) | DRD2DRD4PPARGTP53KMT2A | |
| SCHEMBL29107248 | 0.78 | SIRT2 (0.40) | HTTTP53LMNAPOLBKMT2A | |
| SCHEMBL29107245 | 0.75 | MEN1 (0.51) | PPARGTP53KMT2AGAAMEN1 | |
| SCHEMBL16709169 | 0.74 | MAOA (0.38) | PPARGPOLBKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL16709179 | 0.74 | MAOA (0.42) | DRD2DRD4TP53LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117069742-A | Spiro [ pyridine-thiazolidine ] compound and preparation method and application thereof | 五邑大学 | 2023-11-17 | — | — | CN | disclosed |