Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | GAA | P10253 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
| ▸ | CMA1 | P23946 | 1/20 | 0.30 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28621893 | 0.83 | POLB (0.43) | POLBALDH1A1GAAKMT2AMAPT | |
| SCHEMBL30675225 | 0.75 | PTGDR2 (0.45) | POLBALOX5KDM4ERORC | |
| SCHEMBL28626906 | 0.75 | PTGDR2 (0.45) | POLBALOX5KDM4ERORC | |
| SCHEMBL28628728 | 0.69 | LMNA (0.43) | POLBALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL10180060 | 0.69 | CTSS (0.43) | POLBALDH1A1KMT2AKDM4EESR1 | |
| SCHEMBL2919132 | 0.64 | ACHE (0.42) | POLBALDH1A1GAAKMT2ALMNA | |
| SCHEMBL10181394 | 0.64 | ACHE (0.49) | ALDH1A1GAAKMT2ALMNAKDM4E | |
| SCHEMBL12475116 | 0.63 | ACHE (0.40) | ALDH1A1KMT2AKDM4EESR1RECQL | |
| SCHEMBL2002076 | 0.62 | PPARG (0.50) | POLBKMT2AMEN1LMNAKDM4E | |
| SCHEMBL1996213 | 0.61 | ALDH1A1 (0.50) | ALDH1A1GAAKDM4EESR1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113429332-B | 3-substituted indole derivative, preparation method thereof and application thereof in antitumor drugs | 长春工业大学 | 2023-12-15 | — | — | CN | disclosed |