Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17754399 | 0.84 | KCNH2 (0.40) | MEN1KMT2AMAPTHPGDALDH1A1 | |
| SCHEMBL30810994 | 0.83 | MAOA (0.40) | MEN1KMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL31248444 | 0.83 | CA2 (0.40) | MEN1KMT2AMAPTKCNH2TSHR | |
| SCHEMBL11432311 | 0.83 | ALDH1A1 (0.39) | MEN1KMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL722868 | 0.82 | KCNH2 (0.58) | MEN1KMT2AMAPTHPGDALDH1A1 | |
| SCHEMBL1331369 | 0.82 | KCNH2 (0.58) | MEN1KMT2AMAPTHPGDALDH1A1 | |
| SCHEMBL29131330 | 0.81 | MTNR1A (0.42) | KMT2AMAPTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL31389228 | 0.81 | KCNH2 (0.41) | MEN1KMT2AMAPTLMNAKCNH2 | |
| SCHEMBL31248445 | 0.81 | KCNH2 (0.41) | MEN1KMT2AMAPTLMNAKCNH2 | |
| SCHEMBL31327270 | 0.78 | CA1 (0.54) | MEN1KMT2AMAPTHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117303992-A | Preparation method of polyfunctional group substituted chiral sulfoxide compound | 厦门大学 | 2023-12-29 | — | — | CN | claimed |
| WO-2025133217-A1 | COMPOUNDS | FLINDR THERAPEUTICS B. V. (NL) | 2025-06-26 | — | — | WO | disclosed |
| EP-4543859-A1 | 3-(SULPHONYL OR SULFONIMIDOYL)PROP-2-EN-1-YL]-2-OXO-1,2-DIHYDROPYRIDINE-3-CARBOXAMIDE DERIVATIVES | Flindr Therapeutics B.V. (NL) | 2025-04-30 | — | — | EP | disclosed |
| US-12234207-B2 | Halo-(3-(phenylsulfonyl)prop-1-enyl)pyridine derivative and use thereof | CUREVERSE INCORPORATED (KR) | 2025-02-25 | — | — | US | disclosed |
| CN-112930345-B | Novel halo- (3- (benzenesulfonyl) prop-1-ene) pyridine derivatives and use thereof | 库尔维斯株式会社 | 2024-09-24 | — | — | CN | disclosed |
| CN-117303992-A | Preparation method of polyfunctional group substituted chiral sulfoxide compound | 厦门大学 | 2023-12-29 | — | — | CN | disclosed |
| WO-2023249490-A1 | 3-(SULPHONYL OR SULFONIMIDOYL)PROP-2-EN-1-YL]-2-OXO-1,2-DIHYDROPYRIDINE-3-CARBOXAMIDE DERIVATIVES | IMMAGENE B.V. (NL) | 2023-12-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12234207-B2 | Halo-(3-(phenylsulfonyl)prop-1-enyl)pyridine derivative and use thereof | KEAP1, NFE2L2, NQO1 | MEN1 4692/4885KMT2A 2452/4885MAPT 2326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.