Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1331369 | 1.00 | KCNH2 (0.58) | KCNH2ACHENPSR1POLBNR1I2 | |
| SCHEMBL19822545 | 0.87 | LTA4H (0.46) | KCNH2ACHENPSR1ALDH1A1HPGD | |
| SCHEMBL17754399 | 0.84 | KCNH2 (0.40) | KCNH2NPSR1MAPTALDH1A1TSHR | |
| SCHEMBL31248444 | 0.82 | CA2 (0.40) | KCNH2ACHEPOLBMAPK1MAPT | |
| SCHEMBL11432311 | 0.82 | ALDH1A1 (0.39) | KCNH2ACHEPOLBALDH1A1TSHR | |
| SCHEMBL30810994 | 0.82 | MAOA (0.40) | KCNH2NPSR1ALDH1A1TSHRMEN1 | |
| SCHEMBL29131265 | 0.82 | MEN1 (0.54) | KCNH2POLBMAPK1MAPTALDH1A1 | |
| SCHEMBL29131330 | 0.81 | MTNR1A (0.42) | KCNH2MAPTALDH1A1TSHRKMT2A | |
| SCHEMBL8826150 | 0.81 | KCNH2 (0.53) | KCNH2ACHENPSR1POLBNR1I2 | |
| SCHEMBL31389228 | 0.80 | KCNH2 (0.41) | KCNH2ACHEPOLBMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120051973-A1 | TiO2 NANOSTRUCTURES, MEMBRANES AND FILMS, AND APPLICATIONS OF SAME | UNIVERSITY OF ARKANSAS TECHNOLOGY DEVELOPMENT (US) | 2012-03-01 | — | — | US | claimed |
| US-20110130482-A1 | Process for preparing armatic thiophenyl ketones | PRETOR ROGER | 2011-06-02 | — | — | US | claimed |
| US-7931812-B2 | TiO2 nanostructures, membranes and films, and applications of same | UNIVERSITY OF ARKANSAS TECHNOLOGY DEVELOPMENT FOUNDATION (US) | 2011-04-26 | — | — | US | claimed |
| US-20100255583-A1 | TiO2 nanostructures, membranes and films, and applications of same | UNIVERSITY OF ARKANSAS TECHNOLOGY DEVELOPMENT FOUNDATION (US) | 2010-10-07 | — | — | US | claimed |
| WO-2008060309-A9 | TIO2 NANOSTRUCTURES, MEMBRANES AND FILMS, AND APPLICATIONS OF SAME | UNIV ARKANSAS TECHNOLOGY DEV F (US) | 2009-07-09 | — | — | WO | claimed |
| EP-1993675-A2 | TIO2 NANOSTRUCTURES, MEMBRANES AND FILMS, AND APPLICATIONS OF SAME | University Of Arkansas Technology Development Foundation (US) | 2008-11-26 | — | — | EP | claimed |
| EP-1799638-B1 | PROCESS FOR PREPARING AROMATIC THIOPHENYL KETONES | CIBA HOLDING INC (CH) | 2008-07-30 | — | — | EP | claimed |
| WO-2008060309-A2 | TIO2 NANOSTRUCTURES, MEMBRANES AND FILMS, AND APPLICATIONS OF SAME | UNIVERSITY OF ARKANSAS TECHNOLOGY DEVELOPMENT FOUNDATION (US) | 2008-05-22 | — | — | WO | claimed |
| EP-1799638-A1 | PROCESS FOR PREPARING AROMATIC THIOPHENYL KETONES | CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) | 2007-06-27 | — | — | EP | claimed |
| WO-2006034966-A1 | PROCESS FOR PREPARING AROMATIC THIOPHENYL KETONES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2006-04-06 | — | — | WO | claimed |
| EP-4590685-A1 | NOVEL STABILIZED NUCLEOSIDE PHOSPHATES AND ANALOGUES THEREOF | Janssen Biotech, Inc. (US) | 2025-07-30 | — | — | EP | disclosed |
| WO-2024062413-A1 | NOVEL STABILIZED NUCLEOSIDE PHOSPHATES AND ANALOGUES THEREOF | JANSSEN BIOTECH, INC. (US) | 2024-03-28 | — | — | WO | disclosed |
| US-20210317083-A1 | NOVEL HALO-(3-(PHENYLSULFONYL)PROP-1-ENYL)PYRIDINE DERIVATIVE AND USE THEREOF | CUREVERSE INCORPORATED (KR) | 2021-10-14 | — | — | US | disclosed |
| US-10315990-B2 | Isothiocyanate compounds and isothiocyanate XPO1 protein inhibitor drugs thereof | DRIVINGFORCE THERAPEUTICS (CN) | 2019-06-11 | — | — | US | disclosed |
| US-20180029979-A1 | ISOTHIOCYANATE COMPOUND AND APPLICATION THEREOF | DRIVINGFORCE THERAPEUTICS Co., Ltd. (CN) | 2018-02-01 | — | — | US | disclosed |
| US-4870079-A | ANTICONVULSANTS, ANTAGONISTS OF N-METHYL-D-ASPARTATE | MERCK & CO., INC. (US) | 1989-09-26 | — | — | US | disclosed |
| EP-0264183-A1 | Derivatives of 5-methyl-10,11-dihydro-5H-dibenzo-(a,d) cyclohepten-5,10-imine | MERCK & CO. INC. (US) | 1988-04-20 | — | — | EP | disclosed |
| US-4215069-A | INSECTICIDES | FMC CORPORATION (US) | 1980-07-29 | — | — | US | disclosed |
| US-4200644-A | Arylthiovinylcyclopropanecarboxylate insecticides | FMC CORPORATION (US) | 1980-04-29 | — | — | US | disclosed |
| EP-0003420-A1 | Arylthiovinylcyclopropanecarboxylate insecticide and intermediates therefor | FMC Corporation (US) | 1979-08-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10315990-B2 | Isothiocyanate compounds and isothiocyanate XPO1 protein inhibitor drugs thereof | XPO1, XPOT, XPO4 | KCNH2 3539/4885ACHE 4289/4885NPSR1 4344/4885 |
| US-20180029979-A1 | ISOTHIOCYANATE COMPOUND AND APPLICATION THEREOF | XPO1, XPOT, XPO4 | KCNH2 2468/4885ACHE 3826/4885NPSR1 3938/4885 |
| US-20110130482-A1 | Process for preparing armatic thiophenyl ketones | ACOT7, AGPAT2, COASY | KCNH2 2987/4885ACHE 4609/4885NPSR1 3084/4885 |
| US-20210317083-A1 | NOVEL HALO-(3-(PHENYLSULFONYL)PROP-1-ENYL)PYRIDINE DERIVATIVE AND USE THEREOF | KEAP1, NFE2L2, BACH1 | KCNH2 3763/4885ACHE 3979/4885NPSR1 3057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.