SCHEMBL291326

SCHEMBL291326

[CH2]Cc1cccc2c1[nH]c1ccccc12

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 5/20 0.53
ALDH1A1 P00352 2/20 0.48
HSD17B10 Q99714 2/20 0.48
GPR3 P46089 1/20 0.48
GABRP O00591 2/20 0.47
GABRD O14764 2/20 0.47
GABRA1 P14867 2/20 0.47
GABRB1 P18505 2/20 0.47
GABRG2 P18507 2/20 0.47
GABRB3 P28472 2/20 0.47
GABRA5 P31644 2/20 0.47
GABRA3 P34903 2/20 0.47
GABRA2 P47869 2/20 0.47
GABRB2 P47870 2/20 0.47
GABRA4 P48169 2/20 0.47
GABRE P78334 2/20 0.47
GABRA6 Q16445 2/20 0.47
GABRG1 Q8N1C3 2/20 0.47
GABRG3 Q99928 2/20 0.47
GABRQ Q9UN88 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL159977 0.85 KIF11 (0.50) KIF11ALDH1A1HSD17B10GPR3GABRP
SCHEMBL11141346 0.84 KIF11 (0.57) KIF11ALDH1A1HSD17B10GPR3GABRP
SCHEMBL9935634 0.82 KIF11 (0.55) KIF11ALDH1A1HSD17B10GPR3GABRP
SCHEMBL6048891 0.82 KIF11 (0.47) KIF11ALDH1A1HSD17B10GPR3GABRP
Formaldehyde SCHEMBL491350 0.81 KIF11 (0.59) KIF11ALDH1A1HSD17B10GPR3GABRP
SCHEMBL28555232 0.81 KIF11 (0.46) KIF11ALDH1A1HSD17B10GPR3GABRP
SCHEMBL157116 0.81 KIF11 (0.58) KIF11ALDH1A1HSD17B10GPR3GABRP
SCHEMBL11577428 0.81 KIF11 (0.53) KIF11ALDH1A1HSD17B10GPR3GABRP
SCHEMBL21808458 0.81 KIF11 (0.53) KIF11ALDH1A1HSD17B10GPR3GABRP
SCHEMBL1735965 0.81 KIF11 (0.53) KIF11ALDH1A1HSD17B10GPR3GABRP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114316137-A High refractive index materials 罗门哈斯电子材料有限责任公司 2022-04-12 CN claimed
EP-2630151-B1 USE OF CYCLIC AZABORONATES AS SENSITIVE MATERIALS IN SENSORS INTENDED TO DETECT THE PRESENCE OF PEROXIDES IN A GASEOUS ENVIRONMENT COMMISSARIAT L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2017-04-12 EP claimed
CN-106045894-A 3(4)-Substituted alkoxyphenoxy hydrocarbon PPAR (peroxisome proliferator-activated receptor) agonist and application thereof 天津医科大学 2016-10-26 CN claimed
US-9194853-B2 Use of cyclic azaboronates as sensitive materials in sensors for detecting the presence of peroxides in a gaseous environment COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2015-11-24 US claimed
US-20130260471-A1 USE OF CYCLIC AZABORONATES AS SENSITIVE MATERIALS IN SENSORS FOR DETECTING THE PRESENCE OF PEROXIDES IN A GASEOUS ENVIRONMENT COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2013-10-03 US claimed
EP-1482931-B1 MONO- AND BICYCLIC AZOLE DERIVATIVES THAT INHIBIT THE INTERACTION OF LIGANDS WITH RAGE TRANSTECH PHARMA INC (US) 2011-10-19 EP claimed
US-20090035302-A1 Rage Antagonists As Agents To Reverse Amyloidosis And Diseases Associated Therewith TRANSTECH PHARMA, INC. (US) 2009-02-05 US claimed
CN-1633290-A Mono-and bicyclic pyrrole derivatives inhibiting ligand interaction with higher glycation end product receptors TRANSTECH PHARMA INC (US) 2005-06-29 CN claimed
EP-1482931-A2 MONO- AND BICYCLIC AZOLE DERIVATIVES THAT INHIBIT THE INTERACTION OF LIGANDS WITH RAGE Transtech Pharma, Inc. (US) 2004-12-08 EP claimed
US-20040082542-A1 Azole derivatives and fused bicyclic azole derivatives as therapeutic agents VTV THERAPEUTICS LLC 2004-04-29 US claimed
WO-2003075921-A2 MONO- AND BICYCLIC AZOLE DERIVATIVES THAT INHIBIT THE INTERACTION OF LIGANDS WITH RAGE TRANSTECH PHARMA, INC. (US) 2003-09-18 WO claimed
CN-118244582-A Negative photosensitive resin composition and cured film thereof 罗门哈斯电子材料韩国有限公司 2024-06-25 CN disclosed
CN-114316137-A High refractive index materials 罗门哈斯电子材料有限责任公司 2022-04-12 CN disclosed
CN-114245882-A Photosensitive resin composition, method for producing patterned cured film, interlayer insulating film, covercoat, surface protective film, and electronic component 艾曲迪微系统股份有限公司 2022-03-25 CN disclosed
EP-3929228-A1 BATTERY MATERIAL AND ELECTRODE MATERIAL Nissan Chemical Corporation (JP) 2021-12-29 EP disclosed
US-20040127708-A1 Nitrogen-containing heteroaryl compounds having hiv integrase inhibitory activity SHIONOGI & CO., LTD. (JP) 2004-07-01 US disclosed
EP-1422218-A1 ANTIVIRAL AGENT SHIONOGI & CO., LTD. (JP) 2004-05-26 EP disclosed
US-20040082542-A1 Azole derivatives and fused bicyclic azole derivatives as therapeutic agents VTV THERAPEUTICS LLC 2004-04-29 US disclosed
EP-1375486-A1 NITROGEN-CONTAINING HETEROARYL COMPOUNDS HAVING HIV INTEGRASE INHIBITORY ACTIVITY SHIONOGI & CO., LTD. (JP) 2004-01-02 EP disclosed
WO-2003075921-A2 MONO- AND BICYCLIC AZOLE DERIVATIVES THAT INHIBIT THE INTERACTION OF LIGANDS WITH RAGE TRANSTECH PHARMA, INC. (US) 2003-09-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090035302-A1 Rage Antagonists As Agents To Reverse Amyloidosis And Diseases Associated Therewith AGER, APP, BACE1 KIF11 4876/4885ALDH1A1 3354/4885HSD17B10 4230/4885
US-20040082542-A1 Azole derivatives and fused bicyclic azole derivatives as therapeutic agents AGER, S100A4, S100B KIF11 4690/4885ALDH1A1 3202/4885HSD17B10 4008/4885
US-20040127708-A1 Nitrogen-containing heteroaryl compounds having hiv integrase inhibitory activity DUT, PNP, INMT KIF11 4227/4885ALDH1A1 1123/4885HSD17B10 837/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.