Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6368612 | 0.73 | MGLL (0.44) | CYP11B1CYP11B2 | |
| SCHEMBL2490844 | 0.67 | PARL (0.41) | CYP11B1CYP11B2 | |
| SCHEMBL29829993 | 0.61 | GSK3A (0.44) | CYP11B1CYP11B2GAA | |
| SCHEMBL30951959 | 0.60 | CES1 (0.50) | GAA | |
| SCHEMBL8312129 | 0.60 | ALDH1A1 (0.33) | CYP11B1CYP11B2 | |
| SCHEMBL383639 | 0.60 | CA9 (0.44) | — | |
| SCHEMBL240232 | 0.60 | MGLL (0.44) | — | |
| SCHEMBL7993526 | 0.58 | CYP11B1 (0.48) | CYP11B1CYP11B2GAA | |
| SCHEMBL30577371 | 0.57 | CYP11B1 (0.57) | CYP11B1CYP11B2 | |
| SCHEMBL8178 | 0.57 | KCNN4 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117355523-A | Polycyclic inhibitors of plasma kallikrein | 武田药品工业株式会社 | 2024-01-05 | — | — | CN | disclosed |
| CN-117355521-A | Heteroaryl inhibitors of plasma kallikrein | 武田药品工业株式会社 | 2024-01-05 | — | — | CN | disclosed |