Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 11/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 7/20 | 0.50 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 2/20 | 0.48 |
| ▸ | TEK | Q02763 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29138064 | 0.87 | MPL (0.45) | RAB9ANPC1KDRTEKMAPT | |
| SCHEMBL29138054 | 0.87 | PDE4D (0.45) | RAB9AKDRTEK | |
| SCHEMBL29138086 | 0.83 | KDR (0.62) | RAB9AKMT2ANPC1KDRTEK | |
| SCHEMBL29138090 | 0.81 | MPL (0.44) | KDRTEK | |
| SCHEMBL29138039 | 0.81 | KDR (0.52) | RAB9AMEN1KMT2ANPC1P4HTM | |
| SCHEMBL29138066 | 0.80 | NPC1 (0.51) | RAB9AMEN1KMT2ANPC1KDR | |
| SCHEMBL1264871 | 0.79 | RAB9A (0.55) | RAB9ANPC1KDRTEKNAMPT | |
| SCHEMBL20302273 | 0.76 | RAB9A (0.65) | RAB9AMEN1KMT2ANPC1P4HTM | |
| SCHEMBL29138072 | 0.74 | GRM1 (0.45) | — | |
| SCHEMBL29138040 | 0.73 | POLB (0.44) | KMT2AP4HTMKDRTEKMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117343081-A | MAT2A inhibitor, pharmaceutical composition and application thereof | 南京正大天晴制药有限公司 | 2024-01-05 | — | — | CN | disclosed |