Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | KDR | P35968 | 3/20 | 0.50 |
| ▸ | TEK | Q02763 | 3/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | BRAF | P15056 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | BCR | P11274 | 1/20 | 0.48 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29138039 | 0.87 | KDR (0.52) | NPC1RAB9AMEN1KMT2AKDR | |
| SCHEMBL29138086 | 0.87 | KDR (0.62) | NPC1RAB9AKMT2AKDRTEK | |
| SCHEMBL29138054 | 0.83 | PDE4D (0.45) | RAB9AKDRTEKLCKBRAF | |
| SCHEMBL29138064 | 0.81 | MPL (0.45) | NPC1RAB9AKDRTEKLCK | |
| SCHEMBL29818184 | 0.80 | NPC1 (0.55) | NPC1RAB9AHPGDMEN1KMT2A | |
| SCHEMBL29138058 | 0.80 | RAB9A (0.58) | NPC1RAB9AMEN1KMT2AKDR | |
| SCHEMBL20302217 | 0.79 | CD38 (0.61) | NPC1RAB9AHPGDMEN1KMT2A | |
| SCHEMBL29138090 | 0.78 | MPL (0.44) | KDRTEKLCKBRAFMAPK14 | |
| SCHEMBL29489337 | 0.77 | NPC1 (0.73) | NPC1RAB9AHPGDMEN1KMT2A | |
| SCHEMBL29138040 | 0.72 | POLB (0.44) | KMT2AKDRTEK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117343081-A | MAT2A inhibitor, pharmaceutical composition and application thereof | 南京正大天晴制药有限公司 | 2024-01-05 | — | — | CN | disclosed |