Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | KIF11 | P52732 | 2/20 | 0.57 |
| ▸ | CTSV | O60911 | 1/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.49 |
| ▸ | TUBB | P07437 | 1/20 | 0.49 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.49 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.49 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.49 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.49 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.49 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29145269 | 0.94 | KIF11 (0.65) | KDM4EMAPTATMKIF11CTSV | |
| SCHEMBL30782014 | 0.89 | KDM4E (0.58) | KDM4EMAPTATMKIF11CTSV | |
| SCHEMBL7983972 | 0.86 | KDM4E (0.77) | KDM4EMAPTATMKIF11CTSV | |
| Carbazole SCHEMBL30782024 | 0.81 | ALDH1A1 (0.61) | KDM4EMAPTATMKIF11KMT2A | |
| Carbazole SCHEMBL28310367 | 0.81 | ALDH1A1 (0.61) | KDM4EMAPTATMKIF11KMT2A | |
| Terephthalic Acid SCHEMBL29145288 | 0.80 | TUBB4A (0.53) | KDM4EMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL147263 | 0.78 | PARP1 (0.73) | KDM4EKIF11KMT2AALDH1A1HSD17B10 | |
| SCHEMBL29377098 | 0.78 | PARP1 (0.73) | KDM4EKIF11KMT2AALDH1A1HSD17B10 | |
| SCHEMBL29823892 | 0.78 | KDM4E (0.60) | KDM4EMAPTKIF11KMT2AMEN1 | |
| SCHEMBL70283 | 0.78 | KDM4E (0.60) | KDM4EMAPTKIF11KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117477036-B | Additive, electrolyte and lithium ion battery | 蓝固(淄博)新能源科技有限公司 | 2024-03-05 | — | — | CN | disclosed |
| CN-117477036-A | Additive, electrolyte and lithium ion battery | 蓝固(淄博)新能源科技有限公司 | 2024-01-30 | — | — | CN | disclosed |