Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19995132 | 0.79 | SIGMAR1 (0.44) | SIGMAR1DRD2HTR2ATRPM8HTR2C | |
| SCHEMBL31429831 | 0.77 | SIGMAR1 (0.39) | SIGMAR1DRD2HTR2ATRPM8CYP2C19 | |
| SCHEMBL11077433 | 0.76 | LMNA (0.44) | SIGMAR1DRD2HTR2AHTR2CKCNH2 | |
| SCHEMBL28881800 | 0.74 | SIGMAR1 (0.39) | SIGMAR1ALDH1A1GAACYP2C19CYP3A4 | |
| SCHEMBL28798029 | 0.69 | SIGMAR1 (0.39) | SIGMAR1DRD2HTR2ATRPM8ALDH1A1 | |
| Methyl Alcohol SCHEMBL28796336 | 0.68 | SIGMAR1 (0.42) | SIGMAR1DRD2HTR2ATRPM8ALDH1A1 | |
| SCHEMBL1246125 | 0.67 | SIGMAR1 (0.44) | SIGMAR1DRD2HTR2ATRPM8CYP1A2 | |
| SCHEMBL11220183 | 0.67 | HSD11B1 (0.46) | SIGMAR1DRD2HTR2ATRPM8ALDH1A1 | |
| SCHEMBL9113086 | 0.67 | SIGMAR1 (0.46) | SIGMAR1DRD2HTR2ATRPM8HTR2C | |
| SCHEMBL31545942 | 0.67 | NR3C1 (0.41) | SIGMAR1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117980473-A | Organisms producing less crotonic acid | 环球生物能源公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-117120604-A | Variants of 3-Methylcrotonate Decarboxylase (MDC) | 环球生物能源公司 | 2023-11-24 | — | — | CN | disclosed |