SCHEMBL291849

SCHEMBL291849

COCOC(=O)OCOC

nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.47
SOAT1 P35610 1/20 0.36
TSHR P16473 4/20 0.33
HSD17B10 Q99714 2/20 0.32
LMNA P02545 1/20 0.32
MGAM O43451 2/20 0.30
GAA P10253 2/20 0.30
SI P14410 2/20 0.30
MGAM2 Q2M2H8 2/20 0.30
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17323453 0.91 ALDH1A1 (0.41) ALDH1A1SOAT1
SCHEMBL17323460 0.91 ALDH1A1 (0.41) ALDH1A1SOAT1
SCHEMBL17481739 0.89 ALDH1A1 (0.39) ALDH1A1SOAT1
SCHEMBL807499 0.89
SCHEMBL807505 0.88
SCHEMBL17263569 0.87 ALDH1A1 (0.42) ALDH1A1TSHRHSD17B10LMNAGAA
SCHEMBL10249500 0.87 ALDH1A1 (0.42) ALDH1A1TSHRHSD17B10LMNAGAA
SCHEMBL12994060 0.87 ALDH1A1 (0.38) ALDH1A1
SCHEMBL7055423 0.87
SCHEMBL11986242 0.87 ALDH1A1 (0.38) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 497 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024191025-A1 COSMETIC COMPOSITION COMPRISING CAPSULES OR BEADS 한국콜마주식회사 2024-09-19 WO claimed
WO-2024046605-A1 COMPOUNDS FOR THE DETECTION OF LIGANDROL NATIONAL CENTER FOR SCIENTIFIC RESEARCH "DEMOKRITOS" (GR) 2024-03-07 WO claimed
US-10570088-B2 Blood brain barrier-penetrating oximes for cholinesterase reactivation HUMAN BIOMOLECULAR RES FOUNDATION (US) 2020-02-25 US claimed
US-20180125986-A1 Nitric Oxide Releasing Produgs of Therapeutic Agents SATYAM APPARAO (IN) 2018-05-10 US claimed
US-20170349538-A1 Blood Brain Barrier-Penetrating Oximes for Cholinesterase Reactivation Human BioMolecular Research Foundation (US) 2017-12-07 US claimed
WO-2016151508-A1 METHOD AND APPARATUS FOR THE PRODUCTION OF DIARYL CARBONATE SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-09-29 WO claimed
EP-2727915-B1 Synthesis of deuterated catechols and benzo[d][1,3]dioxoles and derivatives thereof CONCERT PHARMACEUTICALS INC (US) 2016-04-13 EP claimed
EP-2727915-A1 Synthesis of deuterated catechols and benzo[d][1,3]dioxoles and derivatives thereof Concert Pharmaceuticals Inc. (US) 2014-05-07 EP claimed
US-20140051712-A1 BLOOD BRAIN BARRIER-PENETRATING OXIMES FOR CHOLISTENERASES REACTIVATION HUMAN BIOMOLECULAR RESEARCH INSTITUTE 2014-02-20 US claimed
WO-2012083261-A1 BLOOD BRAIN BARRIER-PENETRATING OXIMES FOR CHOLISTENERASES REACTIVATION HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) 2012-06-21 WO claimed
EP-1979362-B1 NOVEL SILANE COMPOUNDS AND USE THEREOF IN ORDER TO FUNCTIONALISE SOLID MEDIA AND IMMOBILISE BIOLOGICAL MOLECULES ON SAID MEDIA COMMISSARIAT ENERGIE ATOMIQUE (FR) 2010-12-15 EP claimed
US-20090005269-A1 Novel Silane Compounds and Their Use in Functionalizing Solid Supports and Immobilizing Biological Molecules on These Supports CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2009-01-01 US claimed
CN-122094698-A Ligands for extrahepatic delivery of siRNA 2026-05-26 CN disclosed
EP-4419513-B1 ANTITUMORAL COMPOUNDS PHARMA MAR SA (ES) 2025-08-27 EP disclosed
EP-4604951-A1 1-(SULFONYL)-N-PHENYLPYRROLIDINE-2-CARBOXAMIDES DERIVATIVES AND USE THEREOF AMIRA THERAPEUTICS, S.L. (ES) 2025-08-27 EP disclosed
US-12384800-B2 Antitumoral compounds PHARMA MAR, S.A. (ES) 2025-08-12 US disclosed
EP-0779312-A2 Manufacturing method for polycarbonate GENERAL ELECTRIC COMPANY (US) 1997-06-18 EP disclosed
EP-0461274-B1 PROCESS FOR CONTINUOUSLY PRODUCING AROMATIC CARBONATE ASAHI CHEMICAL IND (JP) 1994-06-15 EP disclosed
US-5210268-A Ester interchange, catalysis ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1993-05-11 US disclosed
EP-0461274-A1 PROCESS FOR CONTINUOUSLY PRODUCING AROMATIC CARBONATE Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1991-12-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12384800-B2 Antitumoral compounds TP53, TOP1, MCL1 ALDH1A1 144/4885SOAT1 3269/4885TSHR 4670/4885
US-20090005269-A1 Novel Silane Compounds and Their Use in Functionalizing Solid Supports and Immobilizing Biological Molecules on These Supports SELE, ELANE, EPCAM ALDH1A1 374/4885SOAT1 2122/4885TSHR 3246/4885
US-10570088-B2 Blood brain barrier-penetrating oximes for cholinesterase reactivation ACHE, BCHE, PYGB ALDH1A1 1236/4885SOAT1 896/4885TSHR 2012/4885
US-20180125986-A1 Nitric Oxide Releasing Produgs of Therapeutic Agents NOS2, NOS1, NOS3 ALDH1A1 303/4885SOAT1 3454/4885TSHR 2059/4885
US-20140051712-A1 BLOOD BRAIN BARRIER-PENETRATING OXIMES FOR CHOLISTENERASES REACTIVATION BCHE, ACHE, PYGB ALDH1A1 1908/4885SOAT1 279/4885TSHR 2320/4885
US-20170349538-A1 Blood Brain Barrier-Penetrating Oximes for Cholinesterase Reactivation ACHE, BCHE, PYGB ALDH1A1 1236/4885SOAT1 896/4885TSHR 2012/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.