SCHEMBL29201076

SCHEMBL29201076

Fc1ccccc1[SiH](c1ccccc1)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.35
NFE2L2 Q16236 3/20 0.33
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31
TAAR1 Q96RJ0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29214123 0.84 ACHE (0.41) ACHENFE2L2ALDH1A1SMN1; SMN2CES2
SCHEMBL9149994 0.81 CALM1 (0.35) ACHEALDH1A1SMN1; SMN2
SCHEMBL38902 0.71 ALDH1A1 (0.40) ACHEALDH1A1SMN1; SMN2CES2CES1
SCHEMBL19335701 0.70 TSHR (0.43) ACHEALDH1A1
SCHEMBL9360398 0.70 CYP3A4 (0.43) KDM4EALDH1A1SMN1; SMN2
SCHEMBL20101787 0.70 CA2 (0.43) KDM4EALDH1A1SMN1; SMN2
SCHEMBL29201094 0.70 TSHR (0.43) ALDH1A1CES2CES1
SCHEMBL28482232 0.70 ALDH1A1 (0.37) ALDH1A1
SCHEMBL24849476 0.69 NFE2L2 (0.44) ACHENFE2L2ALDH1A1
SCHEMBL31310645 0.69 CES2 (0.39) ACHENFE2L2ALDH1A1SMN1; SMN2CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117660992-A Synthesis method of organosilicon compound containing Si-O bond 新疆大学 2024-03-08 CN disclosed