Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28674845 | 0.75 | — | — | |
| SCHEMBL4679449 | 0.72 | HSD11B1 (0.36) | TSHRALDH1A1 | |
| SCHEMBL8068895 | 0.71 | MAOA (0.35) | MAOAMAOBHDAC9HSD17B3 | |
| SCHEMBL23781284 | 0.71 | PARP1 (0.34) | MAOBALDH1A1KMT2A | |
| SCHEMBL9782897 | 0.71 | KMT2A (0.32) | TP53ALDH1A1KMT2A | |
| SCHEMBL7529245 | 0.70 | CA1 (0.35) | MAOAMAOBHDAC9HSD17B3 | |
| SCHEMBL1697644 | 0.70 | PARP1 (0.36) | MAPTMAOBALDH1A1SIGMAR1KMT2A | |
| SCHEMBL29462779 | 0.70 | SDCBP (0.33) | LMNAHDAC9TSHRMEN1KMT2A | |
| SCHEMBL4734678 | 0.69 | MAOA (0.33) | POLBLMNAMAPTMAOAMAOB | |
| SCHEMBL28546283 | 0.69 | TP53 (0.32) | LMNATP53HDAC9MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2225382-B1 | NEW MALONATE DECARBOXYLASES FOR INDUSTRIAL APPLICATIONS | BASF SE (DE) | 2016-11-09 | — | — | EP | disclosed |
| CN-101878309-B | Malonate decarboxylases for industrial applications | BASF SE (DE) | 2016-01-13 | — | — | CN | disclosed |
| US-20150147800-A1 | MALONATE DECARBOXYLASES FOR INDUSTRIAL APPLICATIONS | BASF SE (DE) | 2015-05-28 | — | — | US | disclosed |
| US-8951750-B2 | Malonate decarboxylases for industrial applications | BASF SE (DE) | 2015-02-10 | — | — | US | disclosed |
| EP-2565274-A1 | New malonate decarboxylases for industrial applications | BASF SE (DE) | 2013-03-06 | — | — | EP | disclosed |
| EP-2565273-A1 | New malonate decarboxylases for industrial applications | BASF SE (DE) | 2013-03-06 | — | — | EP | disclosed |
| US-20100311037-A1 | MALONATE DECARBOXYLASES FOR INDUSTRIAL APPLICATIONS | BASF SE (DE) | 2010-12-09 | — | — | US | disclosed |
| CN-101878309-A | Malonate decarboxylases for industrial applications | BASF SE | 2010-11-03 | — | — | CN | disclosed |
| EP-2225382-A2 | NEW MALONATE DECARBOXYLASES FOR INDUSTRIAL APPLICATIONS | BASF SE (DE) | 2010-09-08 | — | — | EP | disclosed |
| WO-2009068308-A2 | NEW MALONATE DECARBOXYLASES FOR INDUSTRIAL APPLICATIONS | BASF SE (DE) | 2009-06-04 | — | — | WO | disclosed |
| EP-2065470-A1 | New malonate decarboxylases for industrial applications | BASF SE (DE) | 2009-06-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100311037-A1 | MALONATE DECARBOXYLASES FOR INDUSTRIAL APPLICATIONS | ME1, AMD1, GMDS | POLB 1068/4885L3MBTL1 1724/4885LMNA 4196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.