Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CCR3 | P51677 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27121574 | 0.92 | FFAR4 (0.40) | MGLLHSD11B1HPGD | |
| SCHEMBL29201772 | 0.90 | HSD11B1 (0.39) | MGLLHSD11B1TSHRCCR3 | |
| SCHEMBL29201724 | 0.89 | HTR1A (0.38) | MGLLHSD11B1CCR3 | |
| SCHEMBL31524299 | 0.88 | MGLL (0.41) | MGLLHSD11B1TSHR | |
| SCHEMBL28868792 | 0.87 | HSD11B1 (0.40) | MGLLHSD11B1TSHRCCR3HPGD | |
| SCHEMBL29201743 | 0.87 | MGLL (0.42) | MGLLHSD11B1TSHRHPGD | |
| SCHEMBL30015013 | 0.86 | TSHR (0.43) | MGLLHSD11B1TSHRCCR3 | |
| SCHEMBL25221532 | 0.85 | NR3C1 (0.42) | MGLLHSD11B1HPGD | |
| SCHEMBL29384475 | 0.85 | NR3C1 (0.42) | MGLLHSD11B1HPGD | |
| SCHEMBL31255494 | 0.85 | TPSAB1 (0.42) | MGLLHSD11B1TSHRCCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117917416-A | KRAS G12D degradation agent and preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2024-04-23 | — | — | CN | disclosed |