SCHEMBL29224775

SCHEMBL29224775

C=CC(=O)NCCC(=O)Nc1ccccc1B(O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 1/20 0.40
▸ TGM2 P21980 3/20 0.40
▸ MAPK1 P28482 1/20 0.39
▸ ITGB3 P05106 1/20 0.39
▸ ITGAV P06756 1/20 0.39
▸ HDAC3 O15379 5/20 0.38
▸ HDAC1 Q13547 5/20 0.38
▸ KMT2A Q03164 2/20 0.37
▸ CYP2C19 P33261 1/20 0.37
▸ MEN1 O00255 1/20 0.37
▸ HDAC2 Q92769 4/20 0.37
▸ HDAC4 P56524 3/20 0.37
▸ HDAC7 Q8WUI4 3/20 0.37
▸ HDAC10 Q969S8 3/20 0.37
▸ HDAC11 Q96DB2 3/20 0.37
▸ HDAC8 Q9BY41 3/20 0.37
▸ HDAC6 Q9UBN7 3/20 0.37
▸ HDAC9 Q9UKV0 3/20 0.37
▸ HDAC5 Q9UQL6 3/20 0.37
▸ NCOR2 Q9Y618 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29954870 0.81 TGM2 (0.52) TGM2
SCHEMBL236887 0.81 TGM2 (0.52) TGM2
SCHEMBL29224768 0.78 TGM2 (0.46) GAATGM2MAPK1CYP2C19
SCHEMBL6358215 0.73 ALDH1A1 (0.50) GAAMAPK1
SCHEMBL23169263 0.73 CETP (0.62) MAPK1HDAC3HDAC1KMT2AMEN1
SCHEMBL15502171 0.71 KMT2A (0.41) GAAMAPK1KMT2AMEN1
SCHEMBL232004 0.71 ZDHHC20 (0.40) TGM2CYP2C19
SCHEMBL16634646 0.71 TGM2 (0.45) GAATGM2MAPK1KMT2ACYP2C19
SCHEMBL29126030 0.70 MAPT (0.49) TGM2KMT2AMEN1
SCHEMBL16634480 0.68 BTK (0.45) TGM2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12624204-B2 Ultra-high molecular weight polymers and methods of using the same UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2026-05-12 — — US claimed
EP-4395791-A2 ULTRA-HIGH MOLECULAR WEIGHT POLYMERS AND METHODS OF USING THE SAME University of Florida Research Foundation, Inc. (US) 2024-07-10 — — EP claimed
CN-117999081-A Ultra-high molecular weight polymers and methods of use thereof 佛罗里达大学研究基金会公司 2024-05-07 — — CN claimed
WO-2023034765-A2 ULTRA-HIGH MOLECULAR WEIGHT POLYMERS AND METHODS OF USING THE SAME UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2023-03-09 — — WO claimed
US-20230076717-A1 ULTRA-HIGH MOLECULAR WEIGHT POLYMERS AND METHODS OF USING THE SAME UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED 2023-03-09 — — US claimed
US-12624204-B2 Ultra-high molecular weight polymers and methods of using the same UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2026-05-12 — — US disclosed
EP-4395791-A2 ULTRA-HIGH MOLECULAR WEIGHT POLYMERS AND METHODS OF USING THE SAME University of Florida Research Foundation, Inc. (US) 2024-07-10 — — EP disclosed
CN-117999081-A Ultra-high molecular weight polymers and methods of use thereof 佛罗里达大学研究基金会公司 2024-05-07 — — CN disclosed
WO-2023034765-A2 ULTRA-HIGH MOLECULAR WEIGHT POLYMERS AND METHODS OF USING THE SAME UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2023-03-09 — — WO disclosed
US-20230076717-A1 ULTRA-HIGH MOLECULAR WEIGHT POLYMERS AND METHODS OF USING THE SAME UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED 2023-03-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12624204-B2 Ultra-high molecular weight polymers and methods of using the same MUC1, P4HB, UACA GAA 2377/4885TGM2 2490/4885MAPK1 2812/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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