SCHEMBL236887

SCHEMBL236887

C=CC(=O)Nc1ccccc1B(O)O

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 9/20 0.52
PTPN1 P18031 1/20 0.46
PTPN11 Q06124 1/20 0.46
EGFR P00533 2/20 0.42
F13A1 P00488 1/20 0.41
LMNA P02545 1/20 0.41
TGM1 P22735 1/20 0.41
TGM3 Q08188 1/20 0.41
BTK Q06187 1/20 0.39
GSTO1 P78417 1/20 0.39
MAPK3 P27361 1/20 0.39
RORC P51449 1/20 0.39
KDM4E B2RXH2 1/20 0.39
MAPT P10636 1/20 0.39
PKM P14618 1/20 0.39
MMP1 P03956 1/20 0.38
MMP2 P08253 1/20 0.38
MMP9 P14780 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29954870 1.00 TGM2 (0.52) TGM2PTPN1PTPN11EGFRF13A1
SCHEMBL29126030 0.87 MAPT (0.49) TGM2PTPN1PTPN11LMNABTK
SCHEMBL16634480 0.85 BTK (0.45) TGM2PTPN1PTPN11F13A1LMNA
SCHEMBL613090 0.82 TGM2 (0.65) TGM2PTPN1PTPN11EGFRF13A1
SCHEMBL31228347 0.82 TGM2 (0.65) TGM2PTPN1PTPN11EGFRF13A1
SCHEMBL29224775 0.81 GAA (0.40) TGM2
SCHEMBL29860424 0.81 MAPT (0.45) EGFRLMNAKDM4EMAPTPKM
SCHEMBL2249156 0.81 MAPT (0.45) EGFRLMNAKDM4EMAPTPKM
SCHEMBL28416379 0.79 ALDH1A1 (0.44) EGFRLMNAKDM4EMAPTPKM
SCHEMBL29204703 0.79 TGM2 (0.45) TGM2PTPN1PTPN11EGFRF13A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 292 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12624204-B2 Ultra-high molecular weight polymers and methods of using the same UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2026-05-12 US claimed
EP-4720728-A1 COATED SILICONE HYDROGEL CONTACT LENSES AND METHOD FOR MAKING THE SAME Alcon Inc. (CH) 2026-04-08 EP claimed
WO-2025226869-A1 GLUCOSE-RESPONSIVE GLUCAGON-MICELLE FOR THE PREVENTION OF HYPOGLYCEMIA AND METHODS OF USE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-10-30 WO claimed
EP-3927236-B1 MEDIATION OF IN VIVO ANALYTE SIGNAL DEGRADATION SENSEONICS INC (US) 2025-08-27 EP claimed
EP-4599224-A1 RAPID GELLING AQUEOUS MOUNTING MEDIA Life Technologies Corporation (US) 2025-08-13 EP claimed
US-12279862-B2 Mediation of in vivo analyte signal degradation SENSEONICS, INCORPORATED (US) 2025-04-22 US claimed
EP-4493061-A2 CATALYTIC REACTIVE OXYGEN SPECIES SCAVENGER HYDROGEL Senseonics, Incorporated (US) 2025-01-22 EP claimed
CN-118772422-B Recoverable shape memory composite material with super-strong mechanical property based on polyarylether nitrile and preparation method and application thereof 西南石油大学 2024-11-29 CN claimed
WO-2024241239-A1 COATED SILICONE HYDROGEL CONTACT LENSES AND METHOD FOR MAKING THE SAME ALCON INC. (CH) 2024-11-28 WO claimed
US-20240393501-A1 COATED SILICONE HYDROGEL CONTACT LENSES AND METHOD FOR MAKING THE SAME ALCON INC (CH) 2024-11-28 US claimed
WO-2016142301-A1 METHOD AND DEVICE FOR DETECTING IN REAL TIME A SECRETED COMPOUND AND THE SECRETION TARGET, AND USES THEREOF Commissariat à l'énergie atomique et aux énergies alternatives (FR) 2016-09-15 WO claimed
EP-1601999-B1 Holographic sensor and its use SMART HOLOGRAMS LTD (GB) 2013-04-24 EP claimed
EP-2464740-A1 STIMULI RESPONSIVE MEMBRANE Sensile Pat AG (CH) 2012-06-20 EP claimed
US-20120150006-A1 STIMULI RESPONSIVE MEMBRANE SENSILE PAT AG (CH) 2012-06-14 US claimed
WO-2011018752-A1 STIMULI RESPONSIVE MEMBRANE SENSILE PAT AG (CH) 2011-02-17 WO claimed
EP-2284275-A1 Stimuli Responsive Membrane Sensile Pat AG (CH) 2011-02-16 EP claimed
US-20080214912-A1 Blood Glucose Monitoring System And Method GLUCOSE SENSING TECHNOLOGIES, LLC (US) 2008-09-04 US claimed
US-20060063038-A1 Holographic sensor CAMBRIDGE ENTERPRISE LTD (GB) 2006-03-23 US claimed
EP-1601999-A1 HOLOGRAPHIC SENSOR Smart Holograms Limited (GB) 2005-12-07 EP claimed
WO-2004081624-A1 HOLOGRAPHIC SENSOR SMART HOLOGRAMS LIMITED (GB) 2004-09-23 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12624204-B2 Ultra-high molecular weight polymers and methods of using the same MUC1, P4HB, UACA TGM2 2490/4885PTPN1 357/4885PTPN11 592/4885
US-12279862-B2 Mediation of in vivo analyte signal degradation SLC2A1, SLC2A4, SLC2A3 TGM2 3280/4885PTPN1 781/4885PTPN11 578/4885
US-20240393501-A1 COATED SILICONE HYDROGEL CONTACT LENSES AND METHOD FOR MAKING THE SAME CRYAB, P4HB, ILK TGM2 1576/4885PTPN1 4225/4885PTPN11 4372/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.