Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | CKS1B | P61024 | 2/20 | 0.37 |
| ▸ | SKP1 | P63208 | 2/20 | 0.37 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2926594 | 0.87 | HPGD (0.42) | HPGDALDH1A1KDM4EHSD17B10RECQL | |
| SCHEMBL2924918 | 0.83 | P2RX7 (0.44) | HPGDALDH1A1KDM4EHSD17B10NPC1 | |
| SCHEMBL2925505 | 0.81 | CNR1 (0.47) | ALDH1A1TP53MEN1KMT2ACNR1 | |
| SCHEMBL2926527 | 0.75 | RIPK1 (0.47) | HPGDALDH1A1NPC1RAB9ACNR1 | |
| SCHEMBL2925622 | 0.74 | NPC1 (0.46) | HPGDALDH1A1KDM4EHSD17B10NPC1 | |
| SCHEMBL2925886 | 0.73 | TSHR (0.43) | HPGDALDH1A1NPC1MEN1KMT2A | |
| SCHEMBL2853163 | 0.73 | ALDH1A1 (0.45) | ALDH1A1NPC1RAB9APOLB | |
| SCHEMBL2850151 | 0.72 | RAB9A (0.48) | ALDH1A1KDM4ERAB9AKMT2A | |
| SCHEMBL2924923 | 0.71 | HSD11B1 (0.53) | HPGDALDH1A1NPC1TP53RAB9A | |
| SCHEMBL2862995 | 0.70 | ALDH1A1 (0.43) | ALDH1A1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1615698-B1 | NEW AMIDE DERIVATIVES AND PHARMACEUTICAL USE THEREOF | HIGH POINT PHARMACEUTICALS LLC (US) | 2010-09-29 | — | — | EP | claimed |