Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 13/20 | 0.35 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | TGFBR2 | P37173 | 5/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28357157 | 0.81 | GRM2 (0.37) | TGFBR1TGFBR2ADORA2AADORA2BADORA1 | |
| SCHEMBL29248262 | 0.69 | ADORA2A (0.32) | ADORA2AADORA2BADORA1 | |
| SCHEMBL435279 | 0.69 | CYP1A2 (0.38) | — | |
| SCHEMBL150096 | 0.65 | MAOB (0.32) | — | |
| SCHEMBL28360893 | 0.65 | L3MBTL1 (0.35) | — | |
| SCHEMBL31423373 | 0.64 | POLB (0.41) | TGFBR1 | |
| SCHEMBL29248277 | 0.63 | TGFBR1 (0.36) | TGFBR1 | |
| SCHEMBL16469080 | 0.63 | CYP11B1 (0.31) | — | |
| SCHEMBL3607306 | 0.63 | ALDH1A1 (0.35) | — | |
| SCHEMBL11288386 | 0.62 | LMNA (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118317965-A | Adenosine receptor antagonists | 交信医药研发公司 | 2024-07-09 | — | — | CN | claimed |
| CN-118317965-A | Adenosine receptor antagonists | 交信医药研发公司 | 2024-07-09 | — | — | CN | disclosed |