Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5563702 | 0.72 | CYP11B1 (0.39) | GRM4NPC1CYP1A2RAB9A | |
| SCHEMBL5780198 | 0.67 | CYP11B2 (0.47) | MEN1KMT2A | |
| SCHEMBL6998415 | 0.66 | SRPK1 (0.44) | FGFR1 | |
| SCHEMBL2360174 | 0.65 | NR3C1 (0.46) | CYP1A2 | |
| SCHEMBL6087456 | 0.64 | CYP1A2 (0.34) | GRM4MEN1NPC1LMNACYP1A2 | |
| SCHEMBL13604203 | 0.62 | RAB9A (0.53) | MEN1LMNACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1906388 | 0.61 | ALDH1A1 (0.31) | FGFR1GRM4NPC1RAB9A | |
| SCHEMBL30101093 | 0.59 | ALDH1A1 (0.38) | LMNACYP1A2CYP2C9KMT2A | |
| SCHEMBL1906407 | 0.58 | LMNA (0.39) | FGFR1GRM4MEN1NPC1LMNA | |
| SCHEMBL8694456 | 0.57 | GRM4 (0.36) | FGFR1GRM4MEN1NPC1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117924280-B | Substituted thienyl-5-fluoro-1H-pyrazolopyridine compound and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2024-07-12 | — | — | CN | disclosed |
| CN-117924280-B | Substituted thienyl-5-fluoro-1H-pyrazolopyridine compound and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2024-07-12 | — | — | CN | disclosed |
| CN-117924280-B | Substituted thienyl-5-fluoro-1H-pyrazolopyridine compound and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2024-07-12 | — | — | CN | disclosed |
| CN-117924280-A | Substituted thienyl-5-fluoro-1H-pyrazolopyridine compound and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2024-04-26 | — | — | CN | disclosed |
| CN-117924280-A | Substituted thienyl-5-fluoro-1H-pyrazolopyridine compound and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2024-04-26 | — | — | CN | disclosed |
| CN-117924280-A | Substituted thienyl-5-fluoro-1H-pyrazolopyridine compound and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2024-04-26 | — | — | CN | disclosed |