Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2932137 | 0.94 | CCR3 (0.42) | CCR3LMNAHCAR1ALDH1A1 | |
| SCHEMBL2930809 | 0.91 | LMNA (0.40) | LMNAACHEKDM4EALDH1A1 | |
| SCHEMBL3049811 | 0.89 | MEN1 (0.42) | LMNAFAAHACHECSNK1DALDH1A1 | |
| SCHEMBL2930508 | 0.89 | GPR6 (0.34) | HCAR1SMN1; SMN2LPAR2 | |
| SCHEMBL2929411 | 0.89 | ADORA2A (0.41) | ACHEKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL1760873 | 0.88 | FAAH (0.51) | CCR3LMNAMCHR1FAAH | |
| SCHEMBL2930504 | 0.87 | FAAH (0.45) | LMNAFAAHKDM4EALDH1A1 | |
| SCHEMBL2931169 | 0.87 | OGA (0.38) | LMNAFAAHACHELPAR2 | |
| SCHEMBL2930506 | 0.86 | GPR6 (0.38) | LMNAACHEALDH1A1 | |
| SCHEMBL2931482 | 0.85 | MEN1 (0.39) | HCAR1LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2027132-B1 | THIAZOLO-PYRAMIDINE / PYRIDINE UREA DERIVATIVES AS ADENOSINE A2B RECEPTOR ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2010-09-15 | — | — | EP | claimed |